HEALTHY VOLUNTEERS
Clinical trials for HEALTHY VOLUNTEERS explained in plain language.
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New Sjögren's drug candidate tested for safety in Early-Stage trial
Disease control TerminatedThis early-stage study tested a new drug called ASP5502 in healthy adults and people with Sjögren's syndrome, a condition where the immune system attacks moisture-producing glands. The main goal was to check safety and how well the drug is tolerated. The study was terminated, so …
Matched conditions: HEALTHY VOLUNTEERS
Phase: PHASE1 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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Pfizer's weight loss drug for seniors hits early snag
Symptom relief TerminatedThis study tested an experimental drug (PF-07258669) to help older adults who lose weight without trying. The goal was to see if the drug is safe and can improve appetite and weight. The trial was stopped early and included only 7 people aged 60 to 90.
Matched conditions: HEALTHY VOLUNTEERS
Phase: PHASE1 • Sponsor: Pfizer • Aim: Symptom relief
Last updated May 01, 2026 15:42 UTC
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Brain zapping study seeks to unlock secrets of habit breaking
Knowledge-focused TerminatedThis study tested whether a single session of non-invasive brain stimulation (alpha-tACS) could make people more flexible in their habits. Seven healthy adults, including some with risky drinking histories, received either real or fake stimulation while performing a computer task…
Matched conditions: HEALTHY VOLUNTEERS
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 01, 2026 15:54 UTC
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New lung MRI technique breathes life into imaging
Knowledge-focused TerminatedThis study aimed to create better MRI images of the lungs by having healthy volunteers inhale special tracer gases. Researchers tested new hardware and software to improve image quality. The study involved 24 healthy people aged 6 to 75 and did not change their regular medical ca…
Matched conditions: HEALTHY VOLUNTEERS
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 01, 2026 15:41 UTC
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Liquid maribavir study for kids ends early
Knowledge-focused TerminatedThis study looked at two new liquid versions of the drug maribavir, designed for children, to see how well they are absorbed and taste compared to the current tablet. It involved 20 healthy adults and was stopped early. The goal was to gather information, not to treat a disease.
Matched conditions: HEALTHY VOLUNTEERS
Phase: PHASE1 • Sponsor: Shire • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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Early safety check of AMG 378 in healthy volunteers ends early
Knowledge-focused TerminatedThis early-stage study aimed to check if the experimental drug AMG 378 is safe and tolerable in healthy adults aged 18 to 55. Participants received either single or multiple doses of the drug or a placebo. The study was terminated early, so no results on safety or how the drug be…
Matched conditions: HEALTHY VOLUNTEERS
Phase: PHASE1 • Sponsor: Amgen • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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Mindfulness may rewire vaping Teens' brains, study hints
Knowledge-focused TerminatedThis study looked at whether a mindfulness training program could change brain connections in teenagers who vape tobacco. Researchers used brain scans to measure changes before and after training, and also asked teens about their vaping habits. The goal was to see if mindfulness …
Matched conditions: HEALTHY VOLUNTEERS
Phase: NA • Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC
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Healthy volunteers breathe thin air to unlock Body's secrets
Knowledge-focused TerminatedThis study looked at how healthy adults respond to breathing air with less oxygen for up to 7 days. Researchers measured oxygen levels in the blood and checked for changes in red blood cell production and lung pressure. The goal was to understand the body's safety and reactions t…
Matched conditions: HEALTHY VOLUNTEERS
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC
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Healthy volunteers test new drug in early safety trial
Knowledge-focused TerminatedThis early-stage study tested a new drug called iCP-NI in healthy adults to see if it is safe and how the body processes it. Participants received one or more doses of the drug or a placebo by IV. The study was stopped early, and it does not aim to treat any disease.
Matched conditions: HEALTHY VOLUNTEERS
Phase: PHASE1 • Sponsor: Cellivery Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:01 UTC