HEALTHY VOLUNTEERS

This early-stage study tested a new meningococcal B vaccine in 576 healthy people, from infants to adults. Researchers checked for side effects and measured immune responses, comparing the new vaccine to two already-approved ones. The goal was to see if the vaccine is safe and tr…

This early-stage study tested an experimental drug called PF-07258669 in older adults (ages 60-89) who are at risk of malnutrition. The goal was to see if the drug is safe and how it affects the body. Participants took the drug or a placebo for 16 weeks. The study was terminated …

This early-stage study tested a new oral drug, ASP5502, for primary Sjögren's syndrome, an autoimmune condition causing dry eyes and mouth. It involved 116 healthy adults and patients to check safety and how the body processes the drug. The study was terminated, but results may g…

This was a very early (Phase 1) study to check if an experimental drug called iCP-NI is safe in healthy adults. The study planned to give the drug or a placebo by IV to 24 people and watch for side effects. However, the study was terminated early, so results are limited.

This study surveyed teens aged 13–18 and their parents to learn about vaping habits, attitudes, and mental health. Participants answered anonymous questions online about vaping, drug use, mood, and social influences. The goal was to better understand why teens vape and how parent…

This early-stage study tested two new powder formulations of the drug maribavir, designed to be mixed into a liquid for children. Twenty healthy adults took both the new liquid forms and the current tablet to compare how the drug is absorbed, how food affects it, and which versio…

This study tested whether inhaling special tracer gases (xenon and perfluoropropane) can improve MRI images of the lungs. It involved 24 healthy volunteers aged 6 to 75. The goal was to develop better imaging hardware and software, not to treat any disease. The study was terminat…

This early-phase study tested whether a new radioactive drug called [11C]MC1 can help PET scans show inflammation in the body. It included healthy volunteers and people with rheumatoid arthritis or inflammatory myositis. The study was terminated early, so results are limited.

This early-stage study tested the safety and tolerability of a new drug called AMG 378 in 48 healthy adults aged 18 to 55. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moved through the body. The study was termina…

This study tested three portable inhaler devices in 10 healthy adults to see how accurately they measure airflow and record breaths. No medication was used—only a harmless salt solution. The goal was to compare device performance and user comfort, not to treat any disease.

This study aimed to find substances in blood and urine that could signal kidney damage earlier than current tests. Researchers compared samples from healthy volunteers, people with low fluid levels, those at high risk for kidney failure, and patients with acute kidney failure. Th…

This study tested whether a single session of non-invasive brain stimulation (alpha-tACS) could make people more flexible in their habits. Researchers compared real stimulation to a fake version in 7 healthy adults and heavy drinkers. The study was terminated early, so results ar…

This study tested a radiofrequency-based treatment on the skin of healthy volunteers and people with hidradenitis suppurativa (a painful skin condition). The main goal was to see if the treatment is safe and tolerable. The study was stopped early, but it aimed to understand how t…

This study looked at how healthy adults respond to breathing air with less oxygen for up to 7 days. Researchers measured oxygen levels in the blood, red blood cell production, and lung pressure to understand the body's adjustments. The goal was to define safety and basic response…

This study tested whether ultraviolet (UV-C) light can safely sanitize hands without the need for chemical sanitizers. Twenty-three healthy volunteers with light skin received UV-C or UV-B exposure, and small skin samples were taken to check for DNA damage. The trial was stopped …

This study looked at whether a mindfulness training program could change brain connections in teenagers who vape tobacco. Researchers used brain scans to see if these changes were linked to less vaping. The study was small and ended early, so results are limited.