HEALTHY VOLUNTEERS

This study is testing a new vaccine that aims to protect children against five types of meningococcal bacteria that cause meningitis and blood infections. The trial involves 750 healthy children, toddlers, and infants in three stages, comparing the new vaccine to existing license…

This study tests a new vaccine (MenACYW) to protect against four types of meningococcal bacteria that can cause meningitis and bloodstream infections. About 1,600 healthy children and teens aged 2 to 17 in China will receive either the new vaccine or a currently approved one. Res…

This study tests a new mRNA vaccine designed to protect against a potential pandemic flu caused by the H5 virus. About 720 healthy adults aged 18 and older will receive either a high, medium, or low dose of the vaccine or a placebo. The goal is to see if the vaccine is safe and t…

This study tests a new vaccine (PCV21) in healthy infants and toddlers to see if it safely helps their bodies build defenses against pneumococcal bacteria, which can cause serious illnesses like pneumonia and meningitis. About 1,092 babies will receive either the new vaccine or a…

This early-stage study tests a new drug called KK4277 in healthy volunteers and people with lupus (SLE or CLE). The main goal is to see if the drug is safe and how the body processes it. About 157 participants will receive either the drug or a placebo. This is a first step to see…

This early-stage study tests whether black raspberry confections can help prevent oral cancer in 67 healthy volunteers. Researchers will measure how the body absorbs berry compounds and how they affect genes linked to cancer. Participants must be non-smokers and follow a berry-re…

This study looks at how psilocybin, the active ingredient in magic mushrooms, changes brain function in 15 healthy adults. Participants will take psilocybin and have their brain activity measured with EEG and TMS. The goal is to understand how psilocybin affects cognitive control…

This study uses a special camera (OCT) to take detailed pictures of the eyes of 20 healthy adults. The goal is to test and improve the camera's software so it can better detect eye diseases in the future. Participants must be over 18 and have no eye problems.

This study at Stanford University tests whether adding ketamine to standard sedation changes the experience of people with major depressive disorder. Fifteen healthy volunteers will receive both ketamine and saline (saltwater) during separate sedation sessions, without knowing wh…

This early-stage study is testing a new drug, budoprutug, in 38 healthy adults aged 18 to 60. The main goal is to see if the drug is safe and how the body processes it when given as a shot or through an IV. Since participants are healthy, this study is not meant to treat any dise…

This early-stage study tests the safety of a new drug called JADE101 in 32 healthy adults aged 18 to 55. Participants receive a single shot of the drug or a placebo and are monitored for side effects and how the drug moves through the body. The goal is to gather initial safety da…

This early-stage study looks at whether sirolimus, an FDA-approved drug, can improve blood flow to the brain in healthy adults aged 45-65, especially those with a genetic risk for Alzheimer's disease. Researchers use MRI scans to measure changes. The goal is to understand how the…

This early-stage study tests the safety and how the body handles a single dose of an experimental drug called ABBV-277 in 32 healthy adults. Participants will be monitored for side effects and drug levels in the blood. The study does not aim to treat any disease.

This study looks at how natural bacteria in the gut might change the way the cholesterol-lowering drug rosuvastatin works. Researchers will track changes in gut bacteria and cholesterol levels in 62 healthy volunteers over about 16 weeks. The goal is to understand why some people…