New triple diabetes pill tested in healthy adults
NCT ID NCT07399470
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study looks at how a new pill that combines three diabetes medicines (gemigliptin, dapagliflozin, and metformin) works in healthy adults. About 58 people will take either the new combination pill or the three drugs separately, then switch. The goal is to see if the combination pill works the same way in the body. This is a Phase 1 trial, so it focuses on safety and how the drug is processed, not on treating a disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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58 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Feb 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy adults between 19 and 50 years of age * People with a body weight within a healthy range * People who do not have serious medical conditions and have been generally healthy in recent years * People whose screening tests (blood tests, urine tests, vital signs, ECG, etc.) show no significant abnormalities * Women of childbearing potential must not be pregnant at screening * Participants must agree to use reliable contraception or abstain from sexual activity during the study and for a short period after the last dose * People who fully understand the study, agree to follow study requirements, and provide written informed consent Exclusion Criteria: * People with a history of significant diseases, such as heart, liver, kidney, lung, neurological, psychiatric, immune, or cancer-related conditions * People with digestive diseases or surgeries that may affect how medicines are absorbed * People with abnormal screening laboratory results, especially related to liver or kidney function * People who drink large amounts of alcohol, use drugs, or smoke heavily * People who have recently taken certain medications, herbal products, or dietary supplements that could interfere with the study * People who have recently participated in another clinical trial, donated blood, or received a blood transfusion * Pregnant or breastfeeding women * People with unstable or serious health conditions that could increase risk or affect study results * Anyone who, in the opinion of the study doctor, is not suitable to participate
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Jeonbuk National University Hospital
Jeonju, Jeollabuk-do, 54907, South Korea
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