Digestive system cancer

This early-stage trial tests whether a stool transplant (FMT) can help cancer patients who develop severe diarrhea or colon inflammation from immune-checkpoint inhibitor drugs. About 40 patients with various cancers will receive the transplant via colonoscopy. The main goal is to…

This study tests the immunotherapy drug atezolizumab in 200 people with advanced solid tumors (breast, lung, GI, and others). Researchers use each person's tumor DNA to see if it predicts a response. Participants get the same dose every 3 weeks. The goal is to see if DNA analysis…

This early-stage study tests a two-part system to find and treat metastatic cancer. First, a radioactive tracer is used to spot tumors on a PET scan. Then, a similar radioactive drug is given to deliver radiation directly to the cancer cells. The goal is to see if this approach i…

This study tests a wearable patch called MultiSense that tracks heart rate and other vital signs for five days after a patient leaves the hospital following major digestive surgery. The goal is to see if the patch allows high-risk patients to be discharged earlier while still cat…

This Phase 2 trial is testing a new drug called Rina-S (rinatabart sesutecan) in about 160 people with advanced gastrointestinal cancers that have spread or cannot be removed. The drug is given alone through an IV, and everyone receives it—no placebo. The study will check if the …

This study tests whether adding AGuIX gadolinium-based nanoparticles to standard brain radiation can better control brain metastases that are at high risk of coming back. About 134 adults with certain cancers (like melanoma, lung, breast, or colorectal) that have spread to the br…

This study is testing a drug called patritumab deruxtecan in people with advanced gastrointestinal cancers that have spread. The drug is given through a vein and aims to shrink tumors. The trial will check how safe the drug is and how many people's cancers respond to treatment. A…

This early-phase study tests a new drug called BL-B01D1 in people with advanced stomach or other solid tumors that have not responded to standard treatments. The main goals are to find a safe dose and check for any side effects. About 96 adults aged 18 to 75 will take part, and r…

This early-stage study tests a new drug, BL-M07D1, in about 26 people with advanced digestive tract or other solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it helps shrink tumors. Particip…

This early-stage trial tests a new drug called QXL138AM in about 100 people with advanced solid tumors (like ovarian, pancreatic, or lung cancer) or multiple myeloma. The drug is designed to help the immune system attack cancer cells. The main goal is to check safety and find the…

This study tests a new drug combination for people with metastatic solid tumors that lack a gene called MTAP. The drugs, BMS-986504 and pemetrexed, aim to stop cancer cells from growing. The trial will check safety and how well the combo works in 72 participants.

This phase 2 trial tests whether a patient's own white blood cells, genetically modified in a lab to recognize and attack their specific tumor mutations, can shrink metastatic cancers. Participants include people with several advanced solid tumors or multiple myeloma who have exh…

This study tests a new therapy where a person's own white blood cells are collected, genetically modified in a lab to recognize and attack cancer cells with a specific mutation (KRAS G12V), and then infused back. Participants also receive chemotherapy and a drug to boost cell act…

This study looks at whether supervised exercise can improve recovery in people who have had surgery for esophageal or gastric cancer. About 171 participants will be assigned to high-intensity interval training, low-intensity continuous training, or usual care for 8 weeks. The goa…

This early-phase trial is testing an experimental drug called 7MW4911 in 200 people with advanced colorectal or other gastrointestinal cancers that have progressed after standard treatments. The main goals are to find a safe dose and to see if the drug can shrink tumors. It is th…

This trial tests whether two approved drugs, dabrafenib and trametinib, can treat rare cancers that have a specific genetic change called BRAF V600. These drugs are already used for melanoma and lung cancer, but researchers want to see if they help people with other cancer types.…

This study is for people with advanced gastrointestinal cancers that are growing despite immunotherapy. Researchers want to see if adding targeted radiation to one tumor can help the immune system attack other tumors throughout the body. About 28 participants will receive radiati…

This study tests whether adding an experimental drug (KQB198) to the standard cancer pill imatinib can shrink or control advanced gastrointestinal stromal tumors (GIST). About 46 adults with a specific gene mutation (KIT or PDGFRA) will receive the combination. The goal is to see…

This study tests a new drug called SKB571 in 120 adults with gastrointestinal tumors. The goal is to see if the drug can shrink tumors and how safe it is. Participants will receive the drug and be monitored for side effects and cancer progression. The study is not yet recruiting.

This study is testing several new experimental drugs (RAS(ON) inhibitors) combined with standard chemotherapy or other targeted therapies in people with advanced colorectal or pancreatic cancer that has spread. The goal is to see if these combinations are safe and can shrink tumo…

This study tracks 150 gastrointestinal cancer patients with a narrowed portal vein who receive a stent to keep the vein open. Researchers will monitor how long the stent stays clear, changes in liver function, nutrition, bleeding risk, and quality of life. The goal is to see if s…

This study tests a new drug, BHB810, in adults with advanced stomach or gastroesophageal junction cancer that has not responded to standard treatments. The drug is given as an IV infusion every two weeks. The main goals are to check safety and find the best dose, while also seein…

This study tests a new drug called DR30206 combined with standard treatments for people with advanced or spreading gastrointestinal cancers, like colorectal cancer. The goal is to see if the combination is safe and can shrink tumors. About 186 adults in China will take part.

This study tests a program called OPTIMISE that helps cancer patients manage other chronic conditions like diabetes or high blood pressure during treatment. It assigns a nurse navigator to improve communication between cancer doctors and primary care doctors. About 340 patients w…

This study tests a new way to give chemotherapy for gastrointestinal cancers like colorectal and stomach cancer. Doctors will adjust the dose of one chemo drug (5-FU) based on how well each patient tolerates it, aiming to give higher doses to those who can handle it without sever…

This trial investigates whether using a device that sends mild electrical pulses to the thigh muscles (neuromuscular electrical stimulation, or NMES) can prevent muscle loss and weakness after abdominal surgery for colorectal or gastric cancer. Some participants will also receive…

This phase I/II trial tests whether vasodilator drugs (isosorbide mononitrate or diltiazem) can prevent blood vessel damage caused by fluoropyrimidine chemotherapy in 60 patients with gastrointestinal cancer. Researchers will monitor blood vessel reactivity using a non-invasive d…

This study tests a new way to give radiation for abdominal cancer. By having patients hold their breath at different points (inhale and exhale) during treatment, doctors aim to deliver a higher dose to the tumor while protecting nearby healthy organs. The study will enroll 15 adu…

This study tests a new drug called DB-1324 in people with advanced or spreading stomach, bowel, or other gastrointestinal cancers that have stopped responding to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumor…

This study tests whether using real-time MRI to guide radiation therapy can better control abdominal cancer that has spread to a few spots. Thirty adults with certain cancers (like colorectal or breast) will receive high-dose, precisely targeted radiation. The goal is to improve …

This study tests whether adjusting chemotherapy doses based on a patient's DPD enzyme activity can reduce severe side effects in people with digestive cancers. About 400 participants with DPD deficiency will receive lower doses of fluoropyrimidine chemo (with oxaliplatin) and be …

This early-phase trial tests a drug called tirapazamine, which becomes active only in low-oxygen (hypoxic) areas of tumors, combined with a standard procedure that blocks blood flow to the tumor (transarterial embolization). The goal is to find the best dose and see if the combin…

This study looks at whether proton therapy can safely treat cancers that return after standard radiation. Proton beams are more targeted than traditional X-rays, so they may deliver stronger doses to the tumor while sparing healthy tissue. Researchers will track side effects and …

This early-phase study tests a new drug called HC010 combined with chemotherapy in people with advanced solid tumors that have spread or cannot be removed. The main goal is to find a safe dose and check for side effects. About 331 participants will join, and researchers will also…

This study compares two methods of giving chemotherapy directly into the abdomen for people whose cancer has spread there (peritoneal carcinomatosis). One method, HIPEC, uses heated chemotherapy circulated during surgery. The other, PIPAC, delivers chemotherapy as a pressurized s…

This early-phase study tests a new drug called BL-M24D1 in 33 people with advanced gastrointestinal or other solid tumors that have spread. The main goals are to check safety, find the right dose, and get a first look at whether the drug shrinks tumors. Participants receive the d…

This early-stage trial is testing a two-part treatment for advanced gastrointestinal cancer: a personalized mRNA vaccine (XH001) plus immune cells trained to attack the cancer. The study will enroll 18 adults whose cancer has not responded to standard treatments. The main goal is…

This study is testing an anti-PD-1 antibody (a type of immunotherapy) alone or combined with low-dose decitabine and/or standard chemotherapy in people whose cancers have come back or not responded to treatment. The trial includes patients with several cancer types, such as lymph…

This early-stage trial tests a new radioactive drug, lutetium BL-ARC001, in 22 people with advanced gastrointestinal or other solid tumors that have spread. The main goals are to check safety, find the right dose, and see early signs of tumor shrinkage. Participants receive the d…

This phase II trial is testing a rotating schedule of two chemotherapy regimens (FOLFOX and FOLFIRI), with or without the immunotherapy nivolumab, in 38 people with advanced HER2-negative gastric or esophageal cancer. The goal is to see if this approach improves tumor shrinkage a…

This early-phase trial tests an oncolytic virus (IDOV-SAFE) in about 89 people with advanced digestive cancers, like colorectal or stomach cancer, that have not responded to standard treatments. The virus is designed to infect and kill cancer cells. Some participants may also rec…

This early-stage study tests whether combining two drugs (sacituzumab govitecan and capecitabine) is safe for people with advanced gastrointestinal cancers that have stopped responding to standard treatments. About 20 adults with stomach, colorectal, or pancreatic cancer will tak…

This early-phase study tests a new treatment called GC203 TIL for people with advanced solid tumors (cancers in organs like the breast, lung, or gut) that have not responded to standard therapies. The treatment uses a patient's own immune cells, which are modified in a lab to bet…

This early-phase trial tests a combination of two drugs, neratinib and fam-trastuzumab deruxtecan (Enhertu), in people with advanced stomach, esophageal, or other gastrointestinal cancers that have a specific marker called HER2. The study aims to find the safest dose and see if t…

This study tests two AI platforms to personalize cancer treatment for people with solid tumors like gastrointestinal or breast cancer. First, a platform called QPOP analyzes a patient's tumor sample to find the best drug combination. Then, another AI called CURATE.AI adjusts the …

This phase 2 trial tests a new drug called LM-302 combined with other cancer treatments in people with advanced gastrointestinal cancers that have a specific marker (CLDN18.2). The study aims to see if the combination can slow tumor growth or shrink tumors. About 276 participants…

This study tests whether doctors can deliver very high doses of radiation to tumors in the abdomen or chest using an MRI-guided machine, while limiting harm to nearby organs. About 60 people with abdominal or lung cancer will take part. The main goal is to see if the treatment ca…

This study is testing whether a combination of blood and stool biomarkers can accurately screen for cancers of the digestive tract, including stomach, esophagus, and colon. Researchers will collect blood and stool samples from 5,000 people aged 45-74 who are already scheduled for…

This large study is testing whether a combined screening approach—using a blood test for DNA markers plus stool tests for hidden blood and inflammation—can catch gastrointestinal cancers earlier and save lives. Researchers will randomly assign 10,000 adults aged 45–74 to either r…

This study tests a dye called CYTALUX (pafolacianine) that attaches to cancer cells and glows under a special camera during surgery. About 50 adults with certain cancers (like esophageal, pancreatic, or gynecologic) will get the dye before surgery. The goal is to see if the glowi…

This study is testing a new type of PET scan that uses special probes to highlight digestive system cancers, such as stomach, liver, colon, and pancreatic cancers. Researchers will enroll 400 adults to see how well this imaging method finds tumors and tracks their response to tre…

This study tests whether a dye called pafolacianine (CYTALUX™) can make cancer cells glow under near-infrared light during surgery. Fifteen adults with gastric, esophageal, or appendiceal cancer will receive the dye before standard surgery. Surgeons will use a special camera to l…

This study tests whether giving people a personalized report about their cancer risk and screening options helps them complete recommended cancer tests. Adults aged 45 to 74 who are at high risk for lung, breast, colorectal, upper gastrointestinal, or liver cancer are invited to …

This study tests a flexible palliative care program for people with advanced heart failure or certain cancers. The program adds more team members—like a social worker or nurse—as symptoms get worse. The goal is to improve quality of life and match care to each person's changing n…

This study tests whether personalized self-management training helps people with gastrointestinal cancer adopt healthier habits like better diet and more exercise. 120 participants will be randomly assigned to either personalized or standard training for 6 weeks. The goal is to s…

This study tests whether taking a short chain fatty acid supplement can reduce gut-related side effects in people receiving radiation therapy for cancers in the abdomen or pelvis. About 122 adults will be randomly assigned to receive either the supplement or a placebo. The goal i…

This study tests whether a special algorithm called PAGODA can reduce unplanned delays during FOLFOX chemotherapy for gastrointestinal cancers like colon, stomach, and esophageal cancer. About 420 participants will be randomly assigned to either standard care or the algorithm-gui…

This study compares a new radiation technique called lattice radiation therapy (LRT) to standard stereotactic body radiation therapy (SBRT) for people with solid tumors that have spread to soft tissues. The goal is to see if LRT shrinks tumors better and helps the immune system f…

This study is testing three different amounts of treadmill walking (90, 150, or 300 minutes per week) in people receiving chemotherapy for colorectal or stomach cancers. The goal is to find a safe and practical exercise level that helps patients complete their full chemotherapy p…

This trial tests an AI-based platform called Gustabor that creates personalized meal plans for cancer patients experiencing taste disorders from chemotherapy. The study includes adults with multiple myeloma or gastrointestinal cancer who have taste changes and mainly eat by mouth…

This study tests whether an AI-based website that gives personalized diet tips and recipes can help cancer patients who experience taste changes during therapy. About 198 adults with certain cancers (like multiple myeloma, melanoma, or GI cancers) will either get the AI tool or a…

This study tests two supportive care programs—meditation and discussion sessions—for people with advanced (stage IV) cancer and their family caregivers. Researchers want to see if these programs can reduce depressive symptoms and improve quality of life. About 400 patient-caregiv…

This study tests whether adding telephone health coaching to a symptom management handbook helps reduce symptom burden and improve quality of life for people with metastatic breast, GI, or melanoma cancer and their caregivers. About 200 participants will be split into two groups:…

This study tests a home-based palliative care program called TIER-PC that adjusts the care team based on a patient's symptoms and ability to function. It includes 60 adults with advanced heart failure or certain cancers living in Manhattan. The program adds more specialists—like …

This study tests whether training emergency room doctors in palliative care can improve quality of life for patients with advanced lung or gastrointestinal cancer. About 200 participants will be split into two groups: one gets standard ER care, the other gets care from a doctor t…

This trial tests whether an 8-week program combining personalized nutrition advice and supervised home-based exercise is feasible for frail patients with advanced digestive cancers. Participants receive weekly visits from an exercise professional and dietitian, along with unsuper…

This study tests whether a telephone-based counseling program can help patients with advanced gastrointestinal cancer and their family caregivers feel better. The program teaches strategies to manage stress and symptoms, and is compared to a standard education and support program…

This study tests a program called BOLSTER, which offers six telehealth sessions with a nurse to help patients with advanced gynecologic or gastrointestinal cancers and their care partners build skills, manage symptoms, and cope with challenges. Participants also get access to a w…

This study tests whether giving iron infusions can improve anemia (low red blood cells) in cancer patients receiving chemotherapy before surgery. About 34 adults with breast, lung, stomach, or urinary cancers will receive iron sucrose infusions. The goal is to raise hemoglobin le…

This pilot study tests whether Tai Chi, alpha-lipoic acid supplements, and acupuncture can help ease chemotherapy-induced peripheral neuropathy (nerve pain, numbness, tingling) in people with gastrointestinal cancer. About 60 participants will try one or more of these approaches …

This study looks at sleep habits in people with gastrointestinal cancer and their sleep partners. It tests two different programs to help improve sleep quality and reduce insomnia. About 152 patient-partner pairs will take part, and their sleep will be tracked using questionnaire…

This study tests whether fucoidan, a supplement from brown seaweed, can prevent or reduce fatigue in people with gastrointestinal or gynecologic cancers who are starting chemotherapy. About 34 participants will receive either fucoidan or a placebo daily for up to 16 weeks. Resear…

This study tests whether using virtual reality (VR) can reduce severe belly pain and improve quality of life in people with digestive tract cancers. 360 participants will be split into three groups: one using a skills-based VR program, one using distracting VR videos, and a contr…

This study looks at whether using a stress ball during chemotherapy can help lower anxiety, fear, and keep heart rate and blood pressure stable in people with gastrointestinal cancers. Sixty patients will be randomly assigned to either squeeze a stress ball for 15 minutes during …

This study tests a program for older adults (65+) with cancer and mild memory issues, along with their spouse or caregiver. Over six video sessions, the pair learns strategies to manage challenges. The goal is to see if the program reduces distress and improves quality of life. A…

This study tests whether a special program of nutritional checks, medication review, and physical therapy can help people aged 75 and older complete their full course of chemotherapy for digestive cancer. About 144 participants will be randomly assigned to receive either the extr…

This study is testing a program that combines exercise, nutrition advice, and mental support for people with gastrointestinal cancer who are getting chemotherapy before surgery. The goal is to see if this program is practical and helps patients feel stronger and recover better af…

This study tests whether a nerve block called the erector spinae plane block can reduce abdominal pain in people with gastrointestinal cancer. Researchers will compare opioid use and hospital stay length between 25 patients who get the block and a matched group who received stand…

This study tests whether giving the chemotherapy drug oxaliplatin over 6 hours instead of the usual 2 hours can prevent or delay nerve damage in people with gastrointestinal cancers. About 60 participants will be randomly assigned to one of two infusion times. The goal is to see …

This study compares three routine pain control methods used during minimally invasive cancer surgery: a nerve block plus local anesthetic, nerve block alone, or local anesthetic alone. About 48 adults having surgery for various cancers will be randomly assigned to one of the thre…

Researchers are studying whether a next-generation radiation delivery system can run a complete treatment workflow while patients hold their breath. The trial enrolls about 20 adults with tumors in the chest or upper abdomen who are already scheduled for stereotactic body radiati…

This study tests whether a video and personal guidance can help Black, Latinx, and older adults with cancer get genetic testing. Genetic testing is often needed to join precision cancer trials. The goal is to make trial enrollment more equitable. About 210 people with gastrointes…

This study is for Black adults newly diagnosed with gastrointestinal cancer. It focuses on ensuring patients receive proper biomarker testing and evidence-based care, helping them find and join clinical trials if they choose, and providing easy-to-understand information about the…

This study tracks 125 cancer patients receiving standard chemotherapy and radiation to understand why they feel tired. Researchers will collect blood, stool, and survey data before, during, and after treatment. The goal is to find patterns that could help predict and manage fatig…

Researchers are studying whether frailty measured before surgery can predict how older adults recover after an operation for gastrointestinal cancer. The trial enrolls 100 people aged 60 and older who are scheduled for elective surgery. Before the operation, each participant rece…

Researchers are studying whether older adults with gastrointestinal cancer who have low muscle mass and strength before surgery recover worse afterward. The study enrolls about 100 people aged 60 and older who are scheduled for elective cancer surgery. Before their operation, par…

This study collects blood and tumor samples from people with gastrointestinal cancers, such as stomach, liver, or colon cancer. Researchers want to learn how the immune system responds to these cancers. Participants give samples over several visits but receive no treatment as par…

This study looks at whether adding a geriatrician (a doctor who specializes in care for older adults) to cancer treatment can improve outcomes for people aged 70 and older with gastrointestinal cancers like stomach, colon, or pancreatic cancer. Researchers will test if an online …

Researchers at Lille University are following 350 people, including cancer patients recently diagnosed with breast, gynecological, testicular or digestive cancer, their caregivers, and healthcare professionals. Over one year, participants answer questionnaires about post-traumati…

This study looks at a treatment called HIPEC, where heated chemotherapy is washed inside the abdomen after surgery to remove tumors. Researchers want to see if lab-grown tumor models can predict how well the chemotherapy works. Sixty adults with cancers that have spread to the ab…

This study aims to create a collection of tissue and blood samples from people with digestive cancers or inflammatory bowel disease (IBD). Researchers will use these samples to build lab models that mimic how tumors grow and respond to treatments. The goal is to better understand…

This study enrolls 7,000 people with various cancers who have had or will have treatment aimed at a cure. Researchers collect blood, tissue, urine, and saliva samples over time to look for tiny bits of cancer DNA left behind. The goal is to find any remaining cancer as early as p…

This study collects blood, tumor, and other tissue samples from up to 1,250 people with head and neck, lung, or gastrointestinal cancers. Researchers want to understand how the immune system changes during cancer treatments, especially immunotherapies. Participants donate samples…

This study looks at whether measuring the amount of certain targeted cancer drugs in the blood can help find the best dose for each patient. It involves adults with advanced digestive cancers like colorectal, liver, and stomach tumors who are already taking these medications. By …

This trial asks whether five advanced AI models can match the treatment recommendations of expert tumor boards for cancer patients. Using 100 standardized synthetic cases across breast, lung, urological, digestive, and gynecological cancers, each AI and two independent tumor boar…

This study looks at whether measuring a patient's energy reserve (fitness) before major cancer surgery can help predict how well they recover. Researchers will use a special exercise test to measure gas exchange and see if it relates to complications after surgery. The goal is to…

This study tests a digital app called the Genetics Adviser for Mainstream Care (GA-Mainstream) that educates cancer patients about genetic testing and delivers their results. Researchers want to see if using the app reduces distress and improves the patient experience compared to…

This study investigates whether the unique bacteria found inside digestive system tumors can help predict how well a patient will respond to neoadjuvant therapy (chemotherapy before surgery). Researchers will analyze tumor samples from 90 adults with pancreatic, gastric, colorect…

This study is collecting information on side effects from proton therapy in 5,000 adults with many types of cancer. Researchers will track both short-term and long-term side effects and link them to the details of each patient's treatment plan. The goal is to better predict who m…

This study aims to collect and analyze tumor samples from 10,000 adults with advanced solid cancers (like breast, lung, or colon cancer) to create a province-wide gene database. The goal is to help doctors identify which targeted drugs or clinical trials might work best for each …

This study tests a new tool called TRTRM that predicts which older cancer patients are at high risk for severe side effects from treatment. Researchers will use the tool to adjust drug doses and monitoring for patients aged 65 and older with solid tumors. The goal is to see if th…

This study is testing whether tiny particles in the blood, called extracellular vesicles, can predict nerve damage caused by chemotherapy. Researchers will follow 120 adults with various cancers who are receiving specific chemo drugs. Participants give blood samples and answer qu…

This study collects tissue and blood samples from 1,500 people with biliary tree cancers, plus healthy volunteers, to look for genetic changes and risk factors. Researchers hope to build models that predict how the cancer develops and responds to treatment. The goal is to better …

This study surveys 500 surgeons and advanced practice providers across the U.S. to see how often they prescribe blood thinners after cancer surgery to prevent dangerous blood clots. The goal is to understand current practices and find ways to improve care. No new treatments are b…

This study watches how people with gastrointestinal or sarcoma cancers do during and after their standard treatments, including radiation. It aims to learn more about side effects and how well the treatments control the cancer. The results will help doctors improve future treatme…

This study will analyze the genes of 25,000 adults who have cancer or are at risk for it. Researchers will use advanced testing to find genetic changes linked to cancer and track health records over time. The goal is to learn more about cancer biology and discover new ways to per…

This study tests a new type of CT scanner called HyperSight, designed to produce clearer images during radiation therapy for cancer. About 50 adults with various cancers will receive their daily radiation using both the new and standard imaging. Researchers will compare image qua…

This early-phase study tests whether a special dye called pafolacianine (CYTALUX™) can make cancer cells glow during surgery for gastrointestinal cancer that has spread in the abdomen. About 10 adults will receive the dye before surgery, and surgeons will check if glowing areas m…

This study is testing whether a blood test that looks for tumor DNA (ctDNA) can find cancer returning earlier than standard scans. About 100 people with different solid tumors will give blood samples after treatment. The goal is to see if early detection can lead to better treatm…

This study follows 327 patients aged 65 and older who have surgery to remove gastrointestinal cancer. Researchers want to find out what factors predict whether patients will have a decline in physical function or quality of life one year later, and how they do over five years. Th…

This study creates a database of information from people diagnosed with colorectal cancer before age 50. Researchers will compare this to data from older patients to find differences and potential causes. Participants complete a risk factor questionnaire and provide medical infor…

This study looks at whether adding an oncology research navigator (ORN) to standard cancer navigation helps patients with cancer. About 686 adults with new cancer appointments will take part. Some will get the usual navigation, while others also get an ORN who helps them find sup…

This study is collecting blood samples from 1,000 people with digestive, gynecologic, or breast cancers to see if pieces of tumor DNA floating in the blood (called ctDNA) can help doctors diagnose cancer, predict how the disease will progress, and check if treatments are working.…

This study tests whether a type of PET scan that looks for a protein called PSMA can find and monitor gastrointestinal cancers, including liver, colon, pancreatic, and bile duct cancers. About 46 adults with newly diagnosed cancer will get the scan before starting standard treatm…