New combo therapy targets liver tumors in early trial
NCT ID NCT02174549
First seen Apr 24, 2026 · Last updated May 22, 2026 · Updated 5 times
Summary
This early-phase study tests a drug called tirapazamine, which becomes active in low-oxygen areas, combined with a procedure that blocks blood flow to liver tumors (embolization). The goal is to find the safest and most effective dose for people with liver cancer or liver-dominant metastatic neuroendocrine tumors. Up to 25 participants with good liver function and limited tumor burden will receive the drug directly into the liver artery before embolization, and their response will be tracked with MRI scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Stanford University
RECRUITINGPalo Alto, California, 94305, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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