Massive cancer gene mapping project aims to unlock new treatments
NCT ID NCT05142033
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will analyze the genes of 25,000 adults who have cancer or are at risk for it. Researchers will use advanced testing to find genetic changes linked to cancer and track health records over time. The goal is to learn more about cancer biology and discover new ways to personalize treatment. No experimental therapies are given—this is a research-only study.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 25,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants with a premalignant or malignant condition and able/willing to consent/participate in the study.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Must be at least 18 years of age * Must be undergoing a workup or being followed for a premalignant condition or have a diagnosis of cancer * Must voluntarily sign and understand the most current IRB-approved consent form prior to study participation Exclusion Criteria: * Participants incapable of understanding the items listed in the consent form and process * Participants with a history of or known psychiatric illness deemed unable to consent or adhere to study requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
6 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Avera Cancer Institute
RECRUITINGSioux Falls, South Dakota, 57105, United States
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Avera Cancer Institute - Aberdeen
RECRUITINGAberdeen, South Dakota, 57401, United States
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Avera Cancer Institute - Marshall
RECRUITINGMarshall, Minnesota, 56258, United States
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Avera Cancer Institute - Mitchell
RECRUITINGMitchell, South Dakota, 57301, United States
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Avera Cancer Institute - Pierre
RECRUITINGPierre, South Dakota, 57501, United States
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Avera Cancer Institute - Yankton
RECRUITINGYankton, South Dakota, 57078, United States
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