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Virtual reality goggles could be new tool against cancer pain

NCT ID NCT04907643

Symptom relief Sponsor: Cedars-Sinai Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using virtual reality (VR) can reduce severe belly pain and improve quality of life in people with digestive tract cancers. 360 participants will be split into three groups: one using a skills-based VR program, one using distracting VR videos, and a control group using a VR headset with simple 2-D content. The goal is to see if VR can be a helpful, drug-free way to manage cancer pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 360 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2021

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have a primary malignancy of the biliary tract, colon, liver, pancreas, peritoneum, rectum, small intestine, or stomach, with no plan for resection during the study period * Tumor types including, but not limited to, adenocarcinoma, squamous cell carcinoma, neuroendocrine tumors, and tumors of mesenchymal origin will be eligible * Have clinically significant visceral pain, measured using the standardized NIH PROMIS GI Pain Scale defined as scoring at least 5 points above the nationally normed score * Ability to read and write in English Exclusion Criteria: * Have a condition that interferes with VR usage, including but not limited to seizures, facial injury precluding safe placement of headset, and visual impairments * Have cognitive impairment that affects protocol participation. This will be done with a three part cognitive assessment during the initial phone call to assess eligibility followed by consent discussion if eligible. * Have brain metastases * Have a prognosis of \<3 months from the time of enrollment per treating oncologist

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Conditions

The condition(s) this trial relates to.

anal canal cancer anal carcinoma anus cancer anus neoplasm appendiceal neoplasm appendix cancer bile duct cancer bile duct carcinoma bile duct neoplasm biliary tract cancer Biliary Tract Neoplasms Cancer Pain carcinoid tumor carcinoma of the ampulla of vater cecum neuroendocrine tumor G1 colon carcinoma colon neuroendocrine tumor G1 colonic neoplasm colorectal cancer colorectal carcinoma digestive system cancer digestive system neoplasm digestive system neuroendocrine neoplasm enterochromaffin cell serotonin-producing pancreatic neuroendocrine tumor esophageal cancer Esophageal Neoplasms exocrine pancreatic carcinoma gallbladder cancer gallbladder neoplasm gastric cancer gastric carcinoma gastric neoplasm gastric neuroendocrine tumor G1 ileal neuroendocrine tumor G1 liver cancer Liver Neoplasms liver neuroendocrine carcinoma malignant colon neoplasm malignant pancreatic neoplasm Neoplasm Metastasis neuroendocrine neoplasm pancreatic neoplasm peritoneum cancer rectal cancer rectal neoplasm rectal neuroendocrine tumor G1 Recurrence small intestinal neuroendocrine tumor G1 small intestine cancer Visceral Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ampullary cancer Anal cancer Anal cancer metastatic Anal cancer recurrent Anal cancer stage III Anal cancer stage IV Anal cancer, stage IIIA Anal cancer, stage IIIB Appendix cancer Bile duct cancer Bile duct cancer recurrent Bile duct cancer stage I Bile duct cancer stage II Bile duct cancer stage III Bile duct cancer stage IV Bile duct cancer stage IVA Bile duct cancer stage IVB Biliary tract cancer Cancer of gastrointestinal tract Cancer pain Carcinoid tumor Carcinoid tumor of cecum Carcinoid tumor of colon Carcinoid tumor of gi system Carcinoid tumor of ileum Carcinoid tumor of large intestine Carcinoid tumor of liver Carcinoid tumor of pancreas Carcinoid tumor of rectum Carcinoid tumor of the small bowel Carcinoid tumor of the stomach Colon cancer Colon cancer stage III Colon cancer stage IV Esophagus cancer Esophagus cancer, recurrent Esophagus cancer, stage I Esophagus cancer, stage II Esophagus cancer, stage III Esophagus cancer, stage IV Gallbladder cancer Gallbladder cancer stage I Gallbladder cancer stage II Gallbladder cancer stage III Gallbladder cancer stage IV Gastric (stomach) cancer Gastrointestinal cancer metastatic Gastrointestinal cancers - anus Gastrointestinal cancers - colorectal Gastrointestinal cancers - liver Gastrointestinal cancers - small intestine Gastrointestinal cancers - stomach Gastrointestinal neoplasms Large intestine cancer Liver cancer Liver cancer stage IIIA Liver cancer stage IIIB Liver cancer stage IIIC Liver cancer stage IV Neuroendocrine tumor Pancreas cancer Pancreas cancer, metastatic Pancreas cancer, recurrent Pancreas cancer, stage III Pancreas cancer, stage IV Peritoneal cancer Peritoneum cancer Rectal cancer Rectum cancer Rectum cancer, recurrent Small intestine cancer Small intestine cancer stage III Small intestine cancer stage IV Small intestine cancer, recurrent Stomach cancer Stomach cancer recurrent Stomach cancer stage III Stomach cancer stage IV Visceral pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

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