STOMACH CANCER

This early-stage trial tests a new drug (CA-4948) combined with standard chemotherapy and immunotherapy for people with untreated stomach or esophageal cancer that cannot be removed by surgery. The study includes two groups: one for HER2-negative cancer and one for HER2-positive …

This study tests a new robotic system with an extra arm for stomach cancer surgery. Ten adults with newly diagnosed stomach cancer will have their surgery done with this robot. The goal is to see if the robot can safely complete the surgery without switching to standard methods.

This study tests a new drug called 3H-10000 in people with advanced lung or stomach cancer that cannot be removed by surgery or has spread. The drug is designed to target and kill cancer cells while limiting harm to healthy cells. The trial aims to find the safest dose and see if…

This early-phase study tests a new treatment called PTC13, which uses a patient's own immune cells (T-cells) engineered to attack cancer cells that have a protein called CEA. The study includes adults with advanced colorectal, stomach, pancreatic, or other solid tumors that have …

This study tests whether two drugs, avutometinib and defactinib, can slow or shrink tumors in people with a specific type of advanced stomach cancer called diffuse gastric cancer. About 27 participants who have already tried at least one standard treatment will receive the drug c…

This study tests a new drug called ivonescimab combined with standard chemotherapy (FOLFOX) in people with advanced HER2-negative stomach or esophagus cancer that has not been treated before. The goal is to see if the combination can stop the cancer from growing for at least 6 mo…

This study looks at whether buying over-the-counter pain relievers or digestive aids can be an early warning sign for 10 types of cancer, including pancreatic, colon, and ovarian cancer. Researchers will compare the shopping habits of 2,900 people—some recently diagnosed with can…

This study aims to improve how doctors see digestive system cancers (like liver, stomach, and pancreatic cancer) using special PET/CT imaging probes. Researchers will test these probes in 400 adults to measure how they spread in the body and how well they find tumors. The goal is…

This study is testing a blood test that looks for DNA signals from 20 different cancers, including lung, breast, and colon cancer. Researchers will see if the test can find cancer early and tell which type it is. In people with lung cancer, the test will also check for any cancer…

This study tests whether using a simple stress ball during chemotherapy can help stomach cancer patients feel less nauseous, anxious, and fatigued. About 52 adults with stomach cancer will be asked to squeeze a stress ball while receiving treatment. Researchers will measure their…

This study tests whether using virtual reality (VR) can reduce severe belly pain and improve daily life in people with digestive tract cancers. 360 participants will be randomly assigned to one of three groups: skills-based VR, distraction VR, or a sham VR. The goal is to see if …

This study collects tissue and blood samples from people with stomach or esophageal cancer, as well as those at high inherited risk, to learn how genes and proteins contribute to these cancers. The goal is to better understand the disease, not to test a new treatment. About 100 p…

This study tests whether a large language model (a type of AI) can help junior doctors write more accurate and efficient cancer treatment reports. 40 junior doctors will be split into two groups: one uses AI assistance, the other uses traditional methods. Their reports will be sc…