Loyalty cards could spot cancer months earlier
NCT ID NCT06447064
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether the things people buy at stores—like pain relievers or digestive aids—could be early warning signs of cancer. Researchers will compare the shopping habits of 2900 people, some diagnosed with cancer and some not, to see if certain purchases happen more often before a diagnosis. The goal is to find cancers like pancreatic or colon cancer earlier, when treatment works best.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,900 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults aged ≥18 years old, who own at least one participating high street retailer loyalty cad in their household. Among these individuals, those who have been diagnosed with any form of cancer as mentioned above (can join the CLOCS-2 as cases, and those who have no prior cancer diagnosis from the list of cancers mentioned above are eligible to join as controls.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (ALL): * Individuals aged \>18 years of age * Individuals must be residing in the United Kingdom at the time of giving informed consent * Individuals must be registered with an NHS GP Practice * Individuals must meet the criteria of ONE of the groups. For example, to be eligible for Group 1 (Cases), individuals must have been diagnosed with one of the following cancer types in the last 24 months: Bladder, colorectal (bowel), endometrial, liver, oesophageal, ovarian, pancreatic, stomach (gastric), uterine, or vulval; whereas for Group 2 (Controls), individuals must not have received a cancer diagnosis of any type in the last 6 years (except where the diagnosis was of non-melanoma skin cancer). * Individuals must be a primary registered cardholder\* of one of the loyalty cards listed below, and consent to share their loyalty card data with the study team * Tesco Clubcard * Boots Advantage Card * Provision of written informed consent * Willing and able to comply with all required study activities * The primary registered card holder, i.e., the person who is named on the loyalty card account, must also enrol into the study, if someone other than the registered primary card holder from the same household, wants to take part in the study. Exclusion Criteria (ALL): * Individuals under the age of 18 years * Non-UK residents, at the time of giving informed consent * Individuals without an eligible loyalty card, or who have no one in their household who has an eligible loyalty card * Individuals who are not the primary registered cardholder in their household and where the primary registered loyalty card holder is not willing to join the study, and/or where the primary registered cardholder does not make purchases for or on behalf of the individual Exclusion Criteria (CASES): • Individuals will not be able to join as a case if: * they have been diagnosed with an eligible cancer type more than 24 months ago (except where the diagnosis was non-melanoma skin cancer). * they have received an ineligible cancer diagnosis within the last 6 years except where the diagnosis was non-melanoma skin cancer). Exclusion Criteria (Controls): • Individuals will not be able to join as a control (Group 2) if: o they have received any cancer diagnosis in the last six years (except where the diagnosis was non-melanoma skin cancer).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Imperial College Healthcare NHS Trust
RECRUITINGLondon, United Kingdom
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