Acute respiratory distress syndrome

Researchers are testing whether regulatory T cells taken from donated thymus tissue can control the dangerous immune overreaction that occurs in severe COVID-19 and acute respiratory distress syndrome (ARDS). The trial enrolls adults aged 18 to 65 who are hospitalized with acute …

Acute respiratory distress syndrome (ARDS) is a life-threatening lung injury that often requires a breathing machine. This trial compares two ways of using that machine: airway pressure release ventilation (APRV), which holds the lungs open longer with brief releases, and convent…

This early-stage trial tests a new antibody called HT31-1 in 24 healthy volunteers to see if it is safe and how the body processes it. The antibody targets a protein linked to inflammation in acute respiratory distress syndrome (ARDS), a severe lung condition often caused by infe…

This study tests a device called PrismaLung+ that removes carbon dioxide from the blood of critically ill patients who are on breathing machines. The trial will include 99 adults with acute respiratory distress syndrome or kidney injury. Half will receive standard care plus the d…

This study tests a breathing machine strategy that adjusts pressure based on lung measurements to protect the right side of the heart in 180 adults with moderate to severe lung failure from pneumonia. The goal is to see if this method reduces heart strain and complications compar…

This trial is testing a new ventilator called INBENTUS VERSATILE in 81 adults who need help breathing. The study checks if the device is safe and works well for conditions like ARDS, pneumonia, and COPD. Participants will use the ventilator for 3 to 48 hours and be monitored unti…

This study tests an experimental drug called recombinant human plasma gelsolin (rhu-pGSN) added to standard care for people with moderate-to-severe acute respiratory distress syndrome (ARDS) caused by pneumonia or other infections. About 600 hospitalized adults will receive eithe…

This trial tests whether a monitor that measures muscle response can guide the dose of the muscle relaxant atracurium in intensive care unit patients who need a continuous drip for more than 48 hours. Researchers will compare a group whose dose is adjusted using the monitor to a …

This study tests whether the steroid dexamethasone, when added to standard care, can lower the chance of death within 90 days for people with a serious lung condition called ARDS caused by sepsis. About 1,474 adults on breathing machines will take part. The goal is to see if this…

This study is testing a device called the Indigo Aspiration System to remove blood clots from leg arteries in people with acute limb ischemia, a condition where a clot suddenly blocks blood flow. About 300 participants will undergo a procedure where the device sucks out the clot.…

This trial tests two strategies for people with moderate-to-severe acute respiratory distress syndrome (ARDS) who need a breathing machine. First, researchers compare a personalized approach to setting airway pressure based on how much lung is recruitable against standard low or …

This pilot study tests whether placing ARDS patients in an upright position in bed can improve their breathing while on a ventilator. Forty adults with ARDS will be randomly assigned to either upright positioning or standard head-of-bed elevation. The main goal is to see if uprig…

This study tests a drug called vadadustat in 1,100 hospitalized adults with acute respiratory distress syndrome (ARDS) caused by infection. Participants take either a low or high dose of vadadustat or a placebo daily for up to 14 days. The goal is to see if the drug reduces death…

This study tests a temporary device that stimulates the diaphragm (the main breathing muscle) in ICU patients on breathing machines. The goal is to see if it helps patients breathe more on their own and recover from lung injury. About 30 adults with severe breathing failure will …

This trial investigates whether placing infants with severe acute respiratory distress syndrome (ARDS) on their stomachs (prone positioning) after surfactant treatment can improve their oxygen levels. The study involves 14 mechanically ventilated infants, comparing oxygenation an…

This Phase 2 trial tests a drug called paridiprubart in hospitalized adults with moderate to severe acute respiratory distress syndrome (ARDS), a serious lung condition. About 200 participants will receive either the drug or a placebo as a single IV dose. The main goal is to see …

This study tests a medicine called vilobelimab in adults hospitalized with moderate to severe acute respiratory distress syndrome (ARDS), a life-threatening lung condition. About 200 participants will receive either the drug or a placebo to see if it improves survival and is safe…

This study tests a drug called bevacizumab in hospitalized adults with acute respiratory distress syndrome (ARDS), a severe lung condition. About 200 participants will receive either the drug or a placebo to see if it improves survival and oxygen levels. The goal is to find a saf…

This study tests several experimental treatments for adults hospitalized with acute respiratory distress syndrome (ARDS), a severe lung condition. About 600 participants will receive either a placebo or an active drug to see if the treatments improve survival and are safe. The go…

This trial tests whether an antibody called IC14 can reduce dangerous lung inflammation in people with acute respiratory distress syndrome (ARDS), a severe condition where the lungs fill with fluid. Hospitalized patients on a ventilator receive either IC14 or a placebo, and resea…

This trial studies adults with moderate-to-severe acute respiratory distress syndrome (ARDS) who need ECMO life support. Researchers aim to classify patients into immune-based subtypes, understand why complications like kidney injury and bleeding occur, and develop a personalized…

This study investigates whether a standardized, full-course management pathway for ECMO can improve outcomes for adults with moderate-to-severe acute respiratory distress syndrome (ARDS). The pathway covers everything from deciding when to start ECMO through weaning and follow-up…

This trial investigates whether different doses and durations of the corticosteroid dexamethasone improve outcomes for adults with acute respiratory distress syndrome (ARDS) who are on a ventilator. Participants are randomly assigned to receive either no steroids, a low or medium…

This study tests whether an inhaled drug called aprotinin can improve outcomes for adults with moderate to severe acute respiratory distress syndrome (ARDS), a life-threatening lung condition. About 156 critically ill patients in intensive care will receive either aprotinin or a …

This study tests whether using a lung imaging tool called EIT to set ventilator pressure (PEEP) can improve survival in patients with moderate-to-severe ARDS. The trial will enroll 2400 adults and compare EIT-guided PEEP to the standard method. The main goal is to see if this app…

This study tests whether a personalized ventilation strategy guided by electrical impedance tomography (EIT) can improve survival in adults with acute respiratory distress syndrome (ARDS). About 574 participants will be randomly assigned to receive either EIT-guided ventilation (…

This trial tests a real-time algorithm-driven system that gives doctors feedback on ventilator settings to protect the lungs of critically ill patients. The study will include 208 adults on breathing machines with acute respiratory distress syndrome (ARDS). The goal is to see if …

This study tests whether a personalized breathing machine strategy can improve survival in people with acute respiratory distress syndrome (ARDS), a severe lung condition. About 1,100 adults on ventilators will be randomly assigned to either standard care or a precision approach …

This study tests whether a single dose of an experimental immune cell therapy called agenT-797, given alongside standard care, can lower the risk of death in adults with severe pneumonia and breathing failure. About 90 people in intensive care will receive either agenT-797 or a p…

This study tests a new drug called GEn-1124 in 52 adults with acute respiratory distress syndrome (ARDS), a severe lung condition. The drug is given as an IV infusion twice daily for 5 days, starting as soon as possible after diagnosis. The main goal is to check if the drug is sa…

This early-phase trial tests a single inhaled dose of a lab-made protein (Rh-KGF-2) in 24 adults with moderate to severe ARDS who are on ventilators. The goal is to see if the drug is safe and tolerable, and to find the right dose. Participants are split into three dose groups, w…

This study tests whether the steroid methylprednisolone can help critically ill patients with severe inflammation from sepsis or acute respiratory distress syndrome (ARDS). About 150 adults will receive a high dose, low dose, or placebo for up to 7 days. Researchers will measure …

This study tests whether using lung ultrasound to personalize ventilator settings can reduce deaths in people with acute respiratory distress syndrome (ARDS). About 538 adults on breathing machines will be assigned to either standard care or a personalized plan based on their lun…

This study compares two ways of positioning patients with severe lung failure (ARDS) who are on a breathing machine: lying on the stomach for more than 48 hours straight versus 16 to 24 hours each day. The goal is to see which approach helps more people survive. About 780 adults …

This study tests whether pirfenidone, a drug already used for a different lung disease, can prevent scarring in patients with severe acute respiratory distress syndrome (ARDS). About 130 people on ventilators will receive either pirfenidone or a placebo through a feeding tube. Th…

This Phase 3 trial tests whether giving the lungs a near-complete rest (apneic ventilation) early after starting ECMO helps people with the most severe form of acute respiratory distress syndrome (ARDS). About 280 participants will be randomly assigned to either near-apneic venti…

This study tests a blood filter called HA380 in 40 critically ill adults (ages 18-65) who need dialysis or ECMO due to severe infection, injury, or major surgery. The filter is added to their life-support circuit to remove inflammatory substances from the blood. Researchers want …

This study tests a new drug called AV-001 in 120 hospitalized adults with pneumonia who need extra oxygen. The drug is given daily for up to 28 days alongside standard care. The goal is to see if it is safe and helps patients recover faster from pneumonia caused by COVID-19 or ot…

This study is testing whether adding umbilical cord stem cells or their secretions to standard care can help people with severe lung injury (ARDS) caused by pneumonia-related sepsis. The goal is to see if these treatments can shorten hospital stays and lower the risk of death. Th…

This phase 3 trial tests whether a single intravenous dose of ExoFlo, made from bone marrow stem cell vesicles, can lower the death rate in hospitalized adults with moderate-to-severe ARDS. About 970 participants will receive either ExoFlo or a placebo. The main goal is to see if…

This early-phase trial tests whether stem cells from umbilical cords are safe for people with moderate to severe acute respiratory distress syndrome (ARDS), a serious lung condition. About 36 adults will receive an injection of these cells to find the safest dose and check for si…

This study tests an experimental drug called YD0743 in adults with sepsis who develop severe lung failure (ARDS) and need a breathing machine. The main goal is to see if the drug helps patients spend fewer days on the ventilator compared to a placebo. About 309 ICU patients will …

This study looks at 40 adults with severe lung injury (ARDS) who need to lie on their stomachs while on a breathing machine. Researchers want to see if feeding through a tube into the stomach or deeper into the small intestine helps patients get better nutrition and recover faste…

This study tests whether setting a breathing machine based on each patient's lung mechanics can lower the chance of death within 60 days for people with acute respiratory distress syndrome (ARDS). It includes both COVID-19 and non-COVID-19 patients. The approach is compared to st…

This study tests whether using only low-dose blood thinners (instead of the standard full-dose) is safe for patients on a life-support machine called ECMO for severe lung failure. The goal is to see if this approach reduces dangerous bleeding while still preventing clots. Forty a…

This study tests whether transplanting healthy gut bacteria (fecal microbiota) can help people with acute lung injury caused by sepsis. Sepsis triggers severe inflammation that often damages the lungs, and current treatments are limited. The trial will compare standard care plus …

This study looks at whether using higher pressure during noninvasive breathing support (a mask that helps you breathe) can help people with pneumonia or ARDS avoid needing a breathing tube. About 700 adults will be randomly assigned to receive either high or low pressure. The mai…

This study tests whether a real-time lung imaging tool called electrical impedance tomography (EIT) can help doctors choose the best ventilator pressure for patients with lung injury after severe trauma or major surgery. The trial will compare EIT-guided pressure settings to the …

This Phase 3 trial tests an experimental drug called STSA-1002 in 406 adults with acute respiratory distress syndrome (ARDS) caused by a viral infection. Participants receive either the drug or a placebo added to standard care. The main goal is to see if the drug lowers the chanc…

This study tests a new ventilation strategy for patients with a specific type of acute respiratory distress syndrome (ARDS) called focal ARDS. The strategy uses lung ultrasound to guide ventilator settings, early prone positioning, and adjustments based on body mass index. The go…

This study looks at whether keeping patients with severe lung failure (ARDS) on their stomachs for 40 hours at a time, instead of the usual 16 hours, can lower the chance of death. About 800 adults on breathing machines will be randomly assigned to one of the two positions. The g…

This study tests whether a special breathing machine called high-frequency oscillation ventilation (HFOV) works better than standard mechanical ventilation for very premature babies (born at 24 to 31 weeks) who have acute respiratory distress syndrome (ARDS). The goal is to see i…

This study looks at whether a simple blood test, called the fibrinogen-to-albumin ratio, can predict if someone with a traumatic brain injury will develop acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers will measure these proteins in the blood of…

This study looks at whether two simple blood test results—the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio—can help predict which children with severe burns will develop acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers will foll…

This study is testing a breathalyzer kiosk that can detect COVID-19, flu, and RSV by analyzing a person's breath. About 100 adults, both with and without symptoms, will breathe into the device, and the results will be compared to standard nasal swab tests. The goal is to see if t…

This study checks how well standard devices measure blood flow in patients on ECMO, a machine that adds oxygen to blood outside the body. About 30 adults on ECMO will have their blood flow measured using different methods, including ultrasound and a leg-raising test. The goal is …

This study checks how well standard devices measure blood flow in 30 adults on ECMO, a machine that pumps and oxygenates blood outside the body. The goal is to see if these monitors give accurate readings during this special situation. Results could help doctors better manage flu…

This trial tests whether giving an inhaled medication called dornase alfa to severely injured patients on breathing machines can lower their risk of developing acute respiratory distress syndrome (ARDS), a serious lung condition. The drug is thought to break down DNA fragments re…

This study tests a mobile app called Blueprint that teaches coping skills to people who survived a serious illness in the ICU. Many survivors face anxiety, depression, and PTSD, but mental health care is hard to access. The app aims to help them manage these symptoms on their own…

This study tests whether low-intensity shockwave therapy or pulsed electromagnetic field therapy, each combined with pelvic floor muscle training, can improve sexual function in women with sexual dysfunction. 90 premenopausal women aged 20-50 will be randomly assigned to one of t…

This study compares two treatments for chronic knee osteoarthritis: shock wave therapy and structured exercise. Forty adults aged 40 and older with persistent knee pain will be randomly assigned to one of the two groups. The goal is to see which approach better reduces pain and i…

This study tests whether safely raising patients with acute respiratory distress syndrome (ARDS) to an upright position (verticalization) is feasible and safe. Researchers will compare upright positioning with standard prone positioning in 32 adults. The goal is to see if upright…

Researchers at Hospital Civil de Guadalajara are observing mechanically ventilated patients with acute respiratory distress syndrome (ARDS) to measure how often a breathing mismatch called reverse trigger occurs. They monitor patients continuously with esophageal manometry from t…

Researchers at Evangelismos Hospital are studying adults who arrive in the emergency department with sudden acute hypoxemic respiratory failure, a condition where the blood oxygen drops dangerously low. The team collects clinical, imaging, physiological, and biological data early…

This study looks at how tilting the body (trunk inclination) changes lung mechanics in 40 adults with moderate to severe ARDS who are on ventilators. Researchers will measure lung pressures and use electrical imaging to see how different positions and ventilator settings affect l…

This study looks at how to adjust breathing machine settings for people with moderate-to-severe ARDS, a serious lung condition. Researchers will use a special imaging technique to see how air and blood flow match up in the lungs. The goal is to find the best settings for each pat…

This study looks at how different levels of positive end-expiratory pressure (PEEP) on a ventilator affect the diaphragm and lungs in ICU patients with respiratory failure. Twenty-five adults on pressure support ventilation will each receive low, medium, and high PEEP for short p…

This study investigates whether a bedside, radiation-free imaging technique called electrical impedance tomography (EIT) can detect changes in lung blood flow in patients with acute respiratory distress syndrome (ARDS). Researchers will give patients inhaled nitric oxide, a gas t…

This study aims to build a digital early-warning system that uses machine learning to predict acute lung injury (ALI) in patients undergoing major liver surgery. By analyzing cardiopulmonary interaction characteristics, the model could help doctors identify at-risk patients early…

This study surveys doctors who use the Liberant system to remove fresh blood clots from leg arteries and veins. About 50 patients aged 22 or older will be treated within 72 hours of their procedure. The goal is to confirm the device is safe and works as intended.

This study looks at how lying on your left side, right side, or back affects lung function in adults with acute respiratory distress syndrome (ARDS) after abdominal surgery. Researchers will use a special imaging technique called electrical impedance tomography to measure how wel…

This study looks at 500 adults with a severe lung condition called ARDS to see if they fall into two different inflammatory groups. By identifying these groups, doctors hope to choose the right treatments—like fluids, breathing support, or steroids—for each patient. The goal is t…

This study will analyze samples from 130 ICU patients with ARDS (a severe lung injury) to better understand why the condition varies so much between people. Researchers will examine lung fluid, blood, and CT scans to identify distinct biological subtypes. The goal is not to test …

This study looks at two different methods for setting the pressure on a breathing machine (ventilator) in people with a serious lung condition called ARDS. The goal is to see which method improves oxygen levels better over 24 hours. About 52 adults with moderate to severe ARDS wi…

This study tests whether advanced monitoring of breathing patterns can help prevent lung damage in intensive care unit (ICU) patients who need a ventilator for reasons other than lung failure, such as coma or sepsis. Researchers will use special sensors to track airway pressure, …

This study looks at how different ways of measuring height affect ventilator settings and lung injury risk in people with acute respiratory distress syndrome (ARDS). Researchers will measure 39 patients' heights using five methods (stadiometer, visual estimation, tape, laser, and…

This study tests a new AI system called IntelliLung that suggests ventilator settings for ICU patients on breathing machines. Researchers will compare how often doctors' settings match the AI's recommendations. About 530 adults on ventilators will take part across multiple hospit…

This study looks at blood from people with ARDS, a severe lung condition with no specific medicines. Researchers will take immune cells from the blood and test a new blocking agent in the lab to see if it can reduce lung damage. The goal is to learn more about the disease and fin…

This study looks at how different sedatives affect the breathing of patients with acute respiratory distress syndrome (ARDS) who are on a ventilator. Twenty adults in the ICU will receive both standard intravenous propofol and inhaled isoflurane (a gas used in anesthesia) for sho…

This study tests whether a simple manual chest compression technique works as well as electrical impedance tomography (a special imaging method) to find the best ventilator pressure for people with acute respiratory distress syndrome (ARDS). Thirty adults on ventilators will have…

This study uses electrical impedance tomography (EIT), a non-invasive imaging method, to measure how air moves between the lungs in patients with acute respiratory distress syndrome (ARDS) who are on ventilators. Researchers aim to detect delays in lung inflation that could help …

This study aims to better understand why some patients with ARDS (a severe lung condition) get very sick while others recover. Researchers will collect blood and lung fluid from 50 ICU patients to study their immune cells and inflammation patterns. The goal is to identify differe…

This study is testing different treatments to reduce major complications and improve survival in 600 adults who need ECMO—a machine that does the work of the heart and lungs. Researchers will compare how well these treatments work in the first 28 days. The goal is to find safer, …

This study is testing a new, non-invasive brain monitor (Neurosteer) in 100 ICU patients who are on breathing machines and sedatives. The monitor is a small device placed on the forehead that measures brain activity. Researchers want to see if it can accurately track levels of se…

This pilot study tests whether sodium bicarbonate (baking soda) can be used safely as a contrast agent to map lung blood flow using electrical impedance tomography (EIT) in adults on breathing machines. Researchers will compare it to standard hypertonic saline in 41 ICU patients.…

This study tests whether using a special tube to measure pressure inside the chest can help doctors set breathing machines better for severely obese patients with acute lung injury. About 40 adults with a BMI over 40 and moderate to severe ARDS will take part. The goal is to see …

This study looks at patients recovering from acute respiratory distress syndrome (ARDS) who are on a breathing machine. Researchers want to see if increasing the pressure in the ventilator (called PEEP) can reduce the effort patients need to breathe on their own, which may protec…

This study tests a computer program that gives doctors step-by-step advice on how to set breathing machines for children with acute respiratory distress syndrome (ARDS). The goal is to see if the tool can be used in multiple hospitals and if doctors follow its recommendations. Up…

This study tests whether a personalized lung volume optimization maneuver can improve heart and lung function in children on ventilators. It includes two groups: children recovering from heart surgery and those with severe respiratory failure. Researchers will adjust ventilator p…

This study observes 500 adults in intensive care with acute respiratory distress syndrome (ARDS) who are on mechanical ventilation. Researchers will use heart ultrasounds and medication data to track how often right heart failure occurs and how it changes over time. The goal is t…

This study is enrolling 4,000 adults in intensive care with ARDS, sepsis, or pneumonia. Researchers will collect blood, urine, and swab samples, plus track recovery for up to a year. The goal is to identify different patient subtypes and find clues that could lead to better treat…

This study looks at whether lowering the amount of liquid food given through a tube before turning a patient onto their stomach (prone position) can reduce stomach problems like bloating or vomiting. The study involves 259 adults in the ICU who are on breathing machines for sever…

This study looks at how certain white blood cells (macrophages) in the lungs respond to inflammation in people with Acute Respiratory Distress Syndrome (ARDS) who are on breathing machines. Researchers will collect lung fluid samples and blood to compare immune responses from dif…

This study looks at 170 adults with severe breathing failure (ARDS) in the ICU. Researchers will take a blood sample to measure a clotting marker and then check if those who develop a pulmonary embolism (a blood clot in the lung) have higher levels. The goal is to see if this blo…

This study tests whether monitoring changes in airway resistance can help doctors decide the best time to suction mucus from the lungs of patients on ventilators. Researchers will use machine learning to analyze data from 258 patients with conditions like ARDS or severe pneumonia…

This study will use a 3D electrical impedance tomography (EIT) device to monitor how lung ventilation and blood flow change when ARDS patients are placed on their stomach (prone position). Researchers will track 30 patients on mechanical ventilation at three time points: lying on…

This study uses cardiac MRI and other tests to examine heart and lung function in 510 COVID-19 survivors who had symptoms like shortness of breath or cough. The goal is to find out why some people have lasting cardiopulmonary problems after COVID-19. Participants will undergo ima…

This study looks at 20 adults with severe acute respiratory distress syndrome (ARDS) who are on a ventilator and placed face-down (prone position). Researchers will use electrical impedance tomography (EIT), a non-invasive imaging tool, to measure lung overdistension and collapse…

This study follows 100 adults who needed ECMO support for severe heart or lung failure. Researchers will track muscle size, strength, and quality of life over time to understand why some patients develop lasting weakness. No new treatments are being tested; the goal is to gather …

This study is observing how prone positioning (lying face down) affects patients with moderate-to-severe ARDS, a serious lung condition. Researchers will track 1000 adults in intensive care to see if factors like lung shape or brain injury influence outcomes. The goal is to learn…

This study explores whether using both lung and brain ultrasound can help doctors choose the best ventilator pressure for patients with acute respiratory distress syndrome (ARDS) and acute brain injury. About 30 critically ill adults on breathing machines will be enrolled. The go…

This study looks at how small airways open during mechanical ventilation in patients with acute respiratory distress syndrome (ARDS). Researchers want to see if an 'avalanche-like' pattern occurs, which could worsen lung injury. 50 adults with moderate-to-severe ARDS will be moni…

This study looks back at medical records of about 59 ICU patients who used a low-flow carbon dioxide removal (ECCO2R) machine for breathing failure. The goal is to describe how the device was used and what happened to patients, including survival and side effects. It does not tes…

This study observes 134 adults having chest surgery to see if the time spent breathing with only one lung is linked to lung problems like pneumonia or ARDS. Researchers will track surgery details and check for complications within the first week after the procedure. The goal is t…

This study aims to observe how often and what types of aerosol medicines are given to ARDS patients on breathing machines. Researchers will collect data from multiple countries to understand current practices and identify gaps in knowledge. The study does not test a new treatment…

This study looks at how two different levels of breathing support (called PEEP) affect lung function in patients with a severe lung condition called ARDS. The researchers want to see if the response differs based on the patient's lung stiffness. They will use a special imaging te…

This study looks at how changing the way a ventilator lets patients breathe out (called RCexp) affects air and blood flow in the lungs of people with ARDS. Researchers will use a special imaging technique (EIT) to measure these changes in 60 adults on ventilators. The goal is to …

This study tracks complications from a lung-opening procedure used in children under 14 with acute respiratory distress syndrome (ARDS) who are on a breathing machine. The procedure, called alveolar opening maneuver with PEEP titration, aims to improve oxygen levels but can cause…

This study looks at how changing the pressure in a breathing machine (ventilator) affects the effort and drive to breathe in 20 ICU patients with severe lung failure. Researchers will test six different pressure levels and measure breathing muscles, lung activity, and oxygen leve…

This study looks at whether closely tracking a patient's breathing effort can help doctors decide the best time to remove a life-support machine called ECMO in people with severe lung failure (ARDS). About 50 adults on ECMO will be randomly assigned to have their breathing monito…

This study is observing 1,000 critically ill ICU patients to learn how their bodies respond to life-threatening infections and injuries. Researchers will collect blood and lung fluid samples to identify biological factors that could lead to earlier diagnosis and new treatments fo…

This study looks at whether giving a paravertebral nerve block during chest surgery can lower the chance of problems like lung infections, collapsed lungs, or breathing failure. Researchers will follow 500 adults having keyhole or robotic lung surgery. The goal is to see if this …

This study looks at how pregnant and non-pregnant people recover after being in the intensive care unit (ICU) for severe COVID-19. Researchers will check for problems with movement, thinking, and mental health 3 to 6 months after leaving the ICU. The goal is to understand the lon…

This study will observe 500 people with Acute Respiratory Distress Syndrome (ARDS) in intensive care to understand what factors influence their recovery and survival. Researchers will track deaths, imaging, lab tests, and ventilator use. The goal is to find patterns that could im…

This registry is tracking 3,000 critically ill patients who receive the CytoSorb blood-filtering device in real-world intensive care settings. The goal is to collect data on how the device is used and whether it relates to patient survival. It covers many conditions like sepsis, …