Could 'lung rest' on ECMO save more lives in severe ARDS?
NCT ID NCT06814340
First seen Apr 26, 2026 · Last updated Jun 19, 2026 · Updated 10 times
Summary
This Phase 3 trial tests whether giving the lungs a near-complete rest (apneic ventilation) early after starting ECMO helps people with the most severe form of acute respiratory distress syndrome (ARDS). About 280 participants will be randomly assigned to either near-apneic ventilation or standard ultra-protective lung ventilation. The goal is to see if this approach reduces lung injury, shortens time on ECMO, and improves survival at 60 days.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Avicenne Hospital
RECRUITINGBobigny, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Brabois Hospital - CHRU Nancy
RECRUITINGNancy, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Orléans
RECRUITINGOrléans, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Tours
RECRUITINGTours, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Croix-Rousse Hospital - HCL
RECRUITINGLyon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Haut Levèque Hospital - CHU Bordeaux
RECRUITINGBordeaux, France
Contact Email: •••••@•••••
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Henri Mondor Hospital
RECRUITINGCréteil, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mercy Hospital - CHR Metz
RECRUITINGMetz, France
Contact Email: •••••@•••••
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North Hospital - APHM
RECRUITINGMarseille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pitié-Salpêtrière Hospital
RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pontchaillou Hospital - CHU Rennes
RECRUITINGRennes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.