University Of Pittsburgh

This study compares a special follow-up care program to usual care for people who had a serious acute kidney injury. The goal is to see if the program helps patients spend more days out of the hospital over 90 days. About 2,145 adults will take part. The program includes extra mo…

This study tests whether using a bedside ultrasound to check a neck blood vessel can help doctors give the right amount of fluid-removing medicine to people hospitalized with severe heart failure. The goal is to reduce hospital readmissions within 30 days and protect the kidneys.…

This study tests whether nicotinamide riboside, a form of vitamin B3, can help children with mild to moderate ulcerative colitis. Researchers will check how many patients can join and complete the study, and look at changes in gut cell energy centers over 6-12 months. The goal is…

This study looks at whether allowing slightly higher blood sugar levels in mothers with diabetes during labor can lower the chance of their newborns having dangerously low blood sugar. About 218 pregnant women with diabetes who plan to deliver vaginally will take part. Researcher…

This study tests ways to prevent sexual violence and heavy drinking among college students who are at higher risk, such as those with a history of sexual violence, LGBTQ+ students, and students with disabilities. Researchers will work with campus health and counseling centers to …

This study tests two types of talk therapy—Cognitive Enhancement Therapy and Enriched Supportive Therapy—to see if they can reduce persistent negative symptoms in people with schizophrenia. Negative symptoms include things like lack of motivation, reduced emotional expression, an…

This study tests whether adjusting the timing of word-practice sessions can help people with aphasia (trouble finding words after a stroke) remember words longer and use them in everyday life. About 32 adults who had a stroke at least 6 months ago will practice naming pictures us…

This study tests treatments designed for older adults (50+) who have had a concussion. The goal is to reduce symptoms like headache, dizziness, and fatigue. Researchers will compare different treatment approaches to see which works best. About 50 people will take part.

This study tests a program called CARES that helps people with cancer manage their symptoms and improve their quality of life. About 1,750 adults with cancer will be randomly assigned to receive CARES or standard care. The program combines screening and stepped support to address…

This study looks at whether yoga can help people who want to quit tobacco by reducing their cravings. About 96 men who are dependent on tobacco will either do yoga or receive standard quitting advice. Researchers will measure cravings and how many people stay tobacco-free for up …

This study tests a brief sleep program for depressed adolescents aged 12-18 who get too little sleep or have irregular sleep patterns. The program uses two sessions and a smartphone app to teach healthy sleep habits. Researchers want to see if it's practical and helpful for impro…

This study aims to find the genetic and immune changes that lead to lung cancer and help it grow. Researchers will collect tissue samples from 6,000 people with lung cancer or suspicious lung masses. The goal is to identify molecular markers that could predict lung cancer risk.

This study creates a registry of medical information from up to 5,000 adults with interstitial lung disease. Researchers will collect past, current, and future health records to better understand these lung conditions. No experimental treatments or procedures are involved—only da…

This study looks at how poor sleep and out-of-sync body clocks change the brain circuits that control reward and self-control in teenagers. Researchers will track sleep, body clock timing, and brain activity in 100 healthy high school students. The goal is to understand why some …

This study aims to learn more about what causes pancreatic cancer by collecting medical history, family history, and blood or urine samples from 10,000 people. Participants include those with pancreatic cancer, those at high risk, and healthy volunteers. The information gathered …

This study looks at a way to help people under 40 who might lose their ability to have children due to cancer or autoimmune disease treatments. Participants have one ovary removed and frozen for future use. The goal is to improve the freezing and maturing process so the tissue ca…

This study is testing a mobile health app designed to help veterans with spinal cord injury and their family caregivers manage stress and improve well-being. About 100 participants will use the app and give feedback to make it more useful. The goal is to see if the app is practic…

This study follows 1500 people with rare genetic brain diseases to learn how these conditions progress over time. Researchers measure thinking, movement, and daily living skills, and look for biomarkers in blood and spinal fluid. The goal is to better understand these disorders a…

This study aims to find the best way to record electrical signals from the stomach using a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS). Researchers will test different stimulation settings and locations in healthy adults to see what tri…

This study tests whether a remote training program can help manual wheelchair users improve their skills. Researchers will first train peer coaches, then enroll 132 wheelchair users to either receive remote feedback or join a waitlist. The goal is to see if remote training boosts…

This study aims to understand the genetic and molecular causes of liver cancer in children. Researchers will analyze DNA and other biological markers from up to 1,600 participants, including children treated for liver tumors and their biological parents or siblings. The goal is t…

This study tests a training program for college health and counseling providers to improve their knowledge and skills in caring for transgender and gender diverse students. The goal is to make these centers more welcoming and accessible, which may help lower rates of sexual viole…