University Of California, San Diego

This early-stage study is testing whether adding specially designed viruses (called bacteriophages) to standard antibiotics can help treat antibiotic-resistant lung infections in adults with cystic fibrosis. The study will enroll 30 participants to first check if this combined tr…

This study is testing if adding a drug called trimethoprim to standard hormone therapy helps men with advanced prostate cancer. Researchers want to see if lowering folate levels in the body at the start of treatment makes the cancer more responsive. The main goal is to check the …

This study aims to see if cancer drugs chosen to match a patient's specific tumor DNA mutations work better than standard treatments. It will involve 280 adults with advanced, hard-to-treat cancers that have spread or cannot be removed by surgery. Researchers will compare how lon…

This study aims to see if a special monitor that tracks both blood sugar and ketones can reduce the side effects of a drug called sotagliflozin for adults with type 1 diabetes. It will test two different doses of the drug in 52 people who manage their insulin with either daily in…

This study compares two different lengths of hormone therapy when combined with radiation treatment for high-risk prostate cancer. Researchers want to see if 6 months of hormone drugs works as well as the standard 18 months at keeping cancer under control while reducing side effe…

This study is testing if a special high-fat, low-carb diet (called a ketogenic diet) can help people with anorexia nervosa manage the difficult thoughts and behaviors linked to their eating disorder. It will compare 40 people on the special diet to 20 people receiving standard tr…

This study is testing whether adding a specific mindfulness training program to ketamine-assisted therapy helps people with opioid addiction who are already on medication treatment. Researchers want to see if this combination reduces opioid use and cravings better than ketamine t…

This study is testing a new system that creates easy-to-read reports from patients' fitness tracker data. The goal is to help primary care doctors give better, more personalized advice about physical activity to patients with borderline or mild high blood pressure. Researchers wi…

This study is testing whether the drug seladelpar can help liver transplant patients who develop ischemic cholangiopathy, a serious complication that damages bile ducts. Ten adult transplant recipients will take the medication daily for one year. Researchers will check if it redu…

This study aims to improve community health by adding two services to a Chicago health center. First, all patients will be routinely screened for substance use. Second, a social network program will help participants connect friends or partners who may need HIV testing, care, or …

This study is testing a new mobile app package designed to help HIV-negative men who have sex with men and use methamphetamine stay on their daily HIV prevention medication (PrEP). Researchers want to see if the app is easy to use and acceptable, and if it helps improve medicatio…

This study is testing a 12-week online exercise program designed to prevent falls in adults aged 60 and older. Sixty participants will be split into two groups: one starts the exercises right away, while the other waits 12 weeks before starting. The goal is to see if this conveni…

This study is testing a program called Safe Night Out that trains bar staff to recognize warning signs of sexual violence and intimate partner violence and safely intervene. Researchers will compare 50 bars in Sacramento, half with the training and half without, by surveying 650 …

This study is testing whether a chatbot powered by artificial intelligence can help new mothers in their recovery after childbirth. Researchers want to see if the chatbot can provide helpful pelvic floor health information and reduce feelings of loneliness. About 130 first-time m…