Personalized cancer treatment: matching drugs to tumor DNA may delay disease worsening

NCT ID NCT07346209

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether drugs chosen to match specific DNA mutations in a patient's tumor can delay cancer worsening better than standard treatments. About 280 adults with metastatic or unresectable solid cancers will be randomly assigned to receive either DNA-matched therapy or standard care. Participants will visit the clinic every two months for checkups and imaging to track their progress.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Molecularly matched therapy (drugs chosen based on tumor DNA mutations)

What this could lead to

If successful, this could show that personalized, DNA-matched drugs delay cancer worsening better than standard treatments.

What could go wrong

This is a Phase 2 trial, so results are early and may not confirm benefit. The approach depends on finding actionable mutations, which may not be possible for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for METASTATIC CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Diego

    La Jolla, California, 92093, United States