University Hospital, Caen

This study looked at whether reviewing and changing the medications of elderly people with mild hyponatremia (low sodium) could help raise their sodium levels and reduce falls. 18 retirement home residents took part, with half getting a medication review by a pharmacologist and t…

This study tested whether using a special monitor (ECOM) during heart surgery helps patients recover faster and have fewer heart problems. 100 adults having planned coronary bypass surgery took part. Half received standard care, while the other half had their fluids and heart fun…

This study tested whether adding a fast-acting blood thinner called cangrelor to the standard drug ticagrelor improves blood flow to the heart after a heart attack. It included 128 adults who had a specific type of heart attack and were already taking ticagrelor. Researchers meas…

This study looked at how well a smart insulin pump system (Smartguard) works in daily life for adults with type 1 diabetes. The system automatically stops insulin delivery when it predicts a low blood sugar. Thirty participants used the system for one year, and researchers tracke…

This study tested the drug sorafenib (Nexavar) in 32 adults with uveal melanoma that had spread to other parts of the body. The main goal was to see if the drug could stop tumors from growing for at least 24 weeks. Researchers also watched for side effects. The trial is now compl…

This study looked at whether a stem cell transplant using a patient's own cells can help control chronic lymphocytic leukemia (CLL) in people under 65 who had not yet been treated. The main goal was to see how long the disease stayed under control. The study found that the transp…

This study tested whether using a non-invasive device (ClearSight) to monitor blood flow and guide fluid management during colorectal surgery could lower the chance of complications. 160 adults having colorectal surgery for polyps, cancer, or Crohn's disease took part. The approa…

This study tested a special PET scan tracer called [18F]FLT to see if it can better diagnose and predict the course of brain tumors in 50 adult patients. The tracer highlights rapidly dividing cells, which are common in aggressive tumors. Researchers compared this new method with…

This study tested whether a special pacemaker feature can accurately diagnose sleep apnea in people with heart problems. Researchers also looked for a link between sleep apnea severity and a hormone called aldosterone. The study involved 66 adults who already needed a pacemaker f…

This early-phase study tested a new radioactive tracer, [18F]-Fludarabine, in 10 adults with untreated chronic lymphocytic leukemia or diffuse large B-cell lymphoma. The goal was to see how the tracer spreads in the body and how well it highlights cancer cells compared to standar…

This study compared two fluids—bicarbonates and saline—to see which better prevents kidney injury caused by contrast dye used in medical scans. The trial involved 300 adults in intensive care who needed contrast dye. Researchers measured how many developed acute kidney injury aft…

This study tested a special laser (pulsed dye laser) to reduce red veins (telangiectasias) on the face and neck in 21 people with scleroderma. Participants received four laser sessions, and doctors checked if the number of veins decreased and if quality of life improved. The goal…

This study tested whether neuro-myo-electrical stimulation (NMES) — a method that uses electrical pulses to make muscles contract — could improve insulin sensitivity in people with type 2 diabetes. Eighteen adults with type 2 diabetes and overweight received NMES on their thigh m…

This study looked at whether walking to the operating room instead of being wheeled on a stretcher can reduce anxiety before surgery. Over 1,200 adults having various surgeries took part. Researchers measured anxiety using a standard questionnaire. The goal was to see if this sim…

This study tested a minimally invasive procedure for carpal tunnel syndrome that uses ultrasound to guide a needle to release pressure on the nerve. 40 adults who did not get better with standard treatments took part. The goal was to see if this approach reduces pain, improves ha…

This study looked at whether giving women glucose drinks during childbirth could shorten labor and reduce the need for instruments like forceps or vacuum. Over 4,000 women took part. The goal was to see if this simple energy boost helps mothers and babies without increasing risks…

This study tested whether wearing virtual reality goggles during a tooth extraction can lower anxiety in adults. 119 people having at least two teeth pulled under local anesthesia were split into two groups: one used VR, the other did not. Anxiety was measured with questionnaires…

This study tested a new treatment for people with hypermobile Ehlers-Danlos syndrome (hEDS), a condition causing loose joints and poor balance. The therapy combined compression garments with specific physical therapy exercises to retrain the body's sense of movement. Forty patien…

This study tested whether giving the numbing drug lidocaine continuously through a vein during weight-loss surgery could reduce pain and the need for strong painkillers afterward. 180 adults scheduled for bariatric surgery took part. Researchers measured how much pain medicine th…

This study tested a faster brain stimulation method (high-frequency rTMS) guided by MRI to treat auditory hallucinations in people with schizophrenia. 72 participants received either real or sham treatment over 2 days. The goal was to see if this approach could reduce the frequen…

This study looked at whether having a dietitian visit patients at home during radiation therapy could improve their overall quality of life. The study included 117 adults with head and neck cancer who were receiving radiation, with or without chemotherapy. The main goal was to se…

This study looked at whether a special education program can improve the quality of life for adults with epilepsy. 80 people took part, learning skills to manage their condition better. The goal was to see if those who joined the program felt a meaningful improvement compared to …

This study looked at 206 French medical residents to see if physical activity levels are linked to anxiety, depression, and burnout. Participants filled out online surveys about their exercise habits and mental health. The goal was to understand these connections, not to test a t…

This study tested whether biofields therapy (a type of magnetic healing) can make common warts on hands and feet disappear. 62 adults were randomly assigned to receive either real or fake therapy. The goal was to see if the real healer's treatment led to more wart cures than the …

This study placed 15 healthy adults in an underground cave for 40 days with no clocks or natural light. Researchers measured how the group's sense of time, sleep patterns, thinking skills, and teamwork changed in this extreme environment. The goal was to understand how humans ada…

This study tested whether pregnant women can have their pre-birth anesthesia checkup via video call instead of traveling to the hospital. About 60 women participated, using a telemedicine cabin or cart near home. The goal was to see if remote exams work as well as in-person visit…

This study looked at how breathing and swallowing interact in people with COPD who were in the intensive care unit for a sudden worsening of their condition. Researchers wanted to see if using a breathing machine (non-invasive ventilation) changes this interaction. Sixteen patien…

This study looked at whether using simulation (practice on mannequins) helps pediatric residents learn neonatal echocardiography (heart ultrasound for newborns) better than standard training. 52 residents from three French hospitals took part. Some received simulation training pl…

This study aimed to create and validate a French version of a questionnaire that measures physical activity levels in people with physical disabilities. Researchers enrolled 50 adults with conditions like stroke, multiple sclerosis, or Parkinson's disease. They tested how well th…

This study looked at whether common heart failure medications are linked to falls in people aged 65 and older. Researchers analyzed a global safety database of 100,000 reports to find patterns. The goal was to identify which drugs might pose a higher fall risk, not to test a new …

This study looked at how brain scans and other tests can help find early signs of Alzheimer's disease. Researchers followed 242 healthy volunteers and people with memory problems over time. They used MRI and PET scans to measure brain changes, thinking skills, and daily activitie…

This study looked at whether virtual reality (VR) tasks, like driving or shopping in a virtual store, can detect thinking and attention problems in people with relapsing-remitting multiple sclerosis (MS) better than standard paper-and-pencil tests. Sixty adults with MS and health…

This study looked at how children with Autism Spectrum Disorder (ASD) form and recall paired memories, like linking a face to a name. Researchers used brain wave recordings (EEG) and memory tests to compare 80 right-handed children aged 10-18, half with ASD and half without. The …

This study looked at whether taking a nap in different places—including a special sleep module—helps healthy adults stay alert and drive better. Forty good sleepers aged 20 to 50 completed driving simulations and alertness tests after napping or resting. The goal was to see which…

This study looked at whether adding hands-on simulation training to standard classroom teaching helps nurses cause fewer problems when inserting needles into dialysis patients' arm connections (AV fistulas). Over 9,600 patients took part. The goal was to see if simulation reduces…

This study looked at how a single dose of the blood thinner apixaban is processed in the body of people with end-stage kidney disease who are on peritoneal dialysis, compared to people with normal kidney function. Researchers measured drug levels in the blood and urine over time.…

This study tested a new way of helping patients breathe after a lung injury. It compared different levels of a special ventilator mode called NAVA to see how it affected breathing and comfort. Fifteen adults in intensive care took part. The goal was to learn how the body responds…

This study tested if giving the antibiotic daptomycin as a shot under the skin works as well as giving it through a vein. Twelve healthy volunteers received the drug both ways to compare how the body absorbs it. The goal is to find a simpler option for patients who have trouble w…

This study looked at whether a single general anesthesia before age 4 affects thinking skills like memory, attention, and flexibility in children aged 9-10. Researchers compared 80 kids who had anesthesia to those who didn't, using computer tasks. The goal is to understand any lo…

This study looked at how low and high frequency magnetic brain stimulation (rTMS) changes brain waves in 30 healthy adults. Participants received both 1 Hz and 20 Hz stimulation in separate sessions, and their brain activity was measured with EEG before and after. The goal was to…

This study looked at how psychological trauma changes the way teenagers' brains handle memory and emotions. Researchers used MRI scans to compare brain activity in 19 teens with PTSD and healthy teens. The goal was to better understand the brain areas involved, not to test a trea…

This study looked at how compression bandages change oxygen levels in the skin of people with leg ulcers that involve both arteries and veins. 38 adults took part. Researchers measured oxygen under the skin before and during compression to see if it helps or hinders healing. The …

This study compared two types of cameras (a newer CZT camera and a standard Anger camera) for taking images of the heart's nerve function in people with stable heart failure. The goal was to see if the newer camera works as well as the standard one. 45 adults with heart failure a…

This study tested whether giving 50% or 100% oxygen during breathing tube removal after general anesthesia leads to fewer drops in oxygen levels. 119 adults having various surgeries took part. The goal was to find the safest oxygen amount to prevent complications like low oxygen …

This study tested a new device called E-celsius, which is a small pill you swallow that measures your body temperature as it travels through your digestive tract. The goal was to see if this pill gives accurate temperature readings compared to standard methods like probes in the …

This study looked at how brief periods of weightlessness during parabolic flights affect spatial memory, brain structure (especially the hippocampus), and stress-related chemicals in the blood. Twenty-four healthy adults completed computer-based memory tests and had brain scans b…

This study tested whether a non-invasive camera can capture images of tiny blood vessels (microcirculation) during brief periods of weightlessness on a special airplane. Sixteen healthy volunteers flew on parabolic flights, experiencing about 21 seconds of zero gravity at a time.…