University Hospital, Caen

This study looked at 128 heart attack patients who had a procedure to open blocked arteries. Some patients received an extra blood thinner called cangrelor on top of standard ticagrelor. The goal was to see if the combination improved blood flow to the heart and reduced leftover …

This study tested whether a device that uses light to monitor blood flow (photoplethysmography) could help doctors manage fluids better during colorectal surgery. The goal was to reduce complications after surgery. 160 adults having colorectal surgery took part. The approach is n…

This study looked at whether reviewing and changing the medications of elderly adults with mild hyponatremia (low sodium) could help raise their sodium levels. 18 retirement home residents over age 65 with low sodium took part. Half had their medications reviewed by a pharmacolog…

This study tested whether a special monitor placed in the breathing tube during heart bypass surgery could help doctors manage fluids and blood flow better. 100 adults having elective coronary bypass surgery were split into two groups: one got standard care, the other used the EC…

This study looked at whether a stem cell transplant can help people under 65 with untreated chronic lymphocytic leukemia (CLL) live longer without their cancer getting worse. 241 participants received either standard treatment or a transplant. The main goal was to see how long th…

This study followed 30 adults with type 1 diabetes who used the Smartguard system, a partially automated insulin pump that can pause insulin delivery when it predicts a low blood sugar. The goal was to see how well the system works in everyday life, focusing on time spent in the …

This study tested the drug sorafenib (Nexavar) in 32 adults with uveal melanoma that had spread to other parts of the body. The goal was to see if the drug could stop tumors from growing for at least 24 weeks. Sorafenib is already used for other cancers, and researchers wanted to…

This study looked at 105 people to find the best blood test values for diagnosing primary hyperaldosteronism, a condition where the adrenal glands make too much aldosterone hormone, causing high blood pressure. Researchers measured aldosterone and renin levels using advanced lab …

This study is adapting and testing a French version of the Athletic Disordered Eating (ADE) scale, a 17-question screening tool designed specifically for athletes. Researchers will enroll 229 athletes aged 15 to 70 who exercise more than 6 hours per week. Participants complete th…

This early-phase study tested a new radioactive tracer called [18F]-Fludarabine for PET scans in 10 people with untreated chronic lymphocytic leukemia or diffuse large B-cell lymphoma. The goal was to see how the tracer spreads in the body and how well it highlights cancer cells.…

This study tested a special PET scan tracer called FLT in 50 adults with brain tumors (gliomas or metastases). The goal was to see if FLT-PET can measure how fast tumor cells are growing, which could help doctors diagnose and predict tumor behavior better than current scans like …

This study tested whether a special algorithm in a pacemaker can accurately diagnose sleep apnea in people with heart problems. Researchers compared the pacemaker's readings to a standard overnight sleep test in 66 participants. They also looked for a link between sleep apnea sev…

This study tested a new scale called SHD-LESS to see if it can detect landing asymmetry in people who had ACL reconstruction surgery. Sixty participants performed a single hop for distance while being recorded on video, and two doctors scored their landing technique. The goal is …

This study tested whether giving a bicarbonate solution (like baking soda) is better than standard saline for preventing kidney injury caused by contrast dye used in imaging. The trial involved 300 adults in intensive care who needed contrast dye. Researchers compared how many pa…

This study looked at whether walking to the operating room instead of being taken on a stretcher can lower anxiety before surgery. Over 1,200 adults having different types of surgery took part. Researchers measured anxiety using a standard questionnaire. The goal was to see if th…

This study tests whether high-frequency magnetic stimulation (rTMS) can reduce auditory hallucinations in people with schizophrenia. Unlike standard low-frequency treatment that takes 15 days, this approach uses 20 Hz stimulation over just 2 days, guided by brain scans for precis…

This study tested whether wearing compression garments and doing specific physiotherapy exercises could improve balance and quality of life in people with hypermobile Ehlers-Danlos syndrome (hEDS). Forty patients with hEDS were followed for a year, first receiving standard care, …

This study tested whether giving women glucose drinks every 3 hours during labor could reduce the need for assisted delivery (forceps or vacuum) and shorten labor. Over 4000 women participated. The idea is that childbirth is like a sports event requiring energy, and oral glucose …

This study tested whether having a dietitian visit patients at home during radiotherapy could improve their quality of life. 117 adults with head and neck cancer took part. The goal was to see if personalized nutrition advice helps patients cope better with treatment side effects…

This study tested whether using electrical stimulation on the thigh muscles could improve how the body uses insulin in people with type 2 diabetes. Eighteen adults with type 2 diabetes who were overweight and on oral medication received a single session and then six days of daily…

This study tested a pulsed dye laser to reduce red veins (telangiectasias) on the face and neck in 21 people with scleroderma. Participants received four laser sessions, and the researchers checked how many veins disappeared, how patients felt about the results, and any side effe…

This study tests whether biofield therapy, a type of energy healing or magnetism, can make common warts on hands and feet disappear. Sixty-two adults with warts for at least 3 months will be randomly assigned to receive either real biofield therapy from a recognized healer or fak…

This study tested a minimally invasive procedure for carpal tunnel syndrome using ultrasound guidance. 40 patients who did not get better with standard treatments received the procedure. Researchers measured pain, hand function, quality of life, and how quickly patients could ret…

This study tested whether using virtual reality (VR) during tooth extractions can lower anxiety in adults. 119 people having at least two teeth pulled under local anesthesia were randomly assigned to either use VR or not. Researchers measured anxiety before and during the procedu…

This study tested whether giving lidocaine through a vein during weight-loss surgery helps patients recover faster and need less strong pain medicine. 180 adults scheduled for bariatric surgery received either lidocaine or a placebo (salt water). Researchers measured how much pai…

This study tested whether a structured education program could improve the quality of life for adults with epilepsy. 80 participants either received individual and group educational sessions or standard care. The goal was to see if learning more about the disease and its manageme…

This study looked at how the heart fills and pumps blood when the body is tilted or exposed to lower body pressure. Researchers compared 30 people with type 1 diabetes and healthy volunteers. They used heart monitoring and ultrasound to measure changes, aiming to understand how d…

This study looked at two ways to improve CPR during cardiac arrest: changing how often rescuers switch (every 2 vs. 4 minutes) and using a device called CPRmeter that gives real-time feedback on chest compressions. Researchers measured the quality of compressions in 51 patients. …

This study investigates whether using lower pressure on the lungs (PEEP) along with extra fluids can prevent blood pressure drops in patients undergoing spine surgery in the knee-chest position. The knee-chest position naturally lowers blood pressure, and standard protective lung…

This study looked at how children with autism (without intellectual disability) form and recall paired memories, like linking a face to a name. Researchers used EEG brain scans and memory tests to compare 74 right-handed children aged 10-18, half with autism and half without. The…

This study looked at whether adding hands-on simulation training to standard classroom teaching helps nurses cause fewer problems when inserting needles into the arm access (arteriovenous fistula) of dialysis patients. About 9600 adults on chronic hemodialysis took part. The goal…

This study tested if a powerful antibiotic called daptomycin works just as well when injected under the skin as when given through a vein. Twelve healthy volunteers received the drug both ways to compare how the body absorbs it. The goal is to find a simpler, more convenient opti…

This study tested two types of cameras—a newer CZT camera and a standard Anger camera—to see how well they measure heart nerve function in people with heart failure. Forty-five patients received a special tracer injection (I-123-MIBG) and were scanned with both cameras. The goal …

This study tested whether taking a nap in different environments, including a special rest module called SOMBOX, helps healthy adults stay alert and drive better. Forty participants each tried four conditions: napping in different settings or resting without napping. Researchers …

This study looked at how breathing and swallowing interact in people with severe COPD who were in the hospital for a sudden worsening of their condition. Researchers wanted to see if using a non-invasive breathing machine (NIV) changes this interaction. Sixteen patients were obse…

This study tested how low (1 Hz) and high (20 Hz) frequency repetitive transcranial magnetic stimulation (rTMS) changes brain activity in 30 healthy adults. Participants received both types of stimulation in separate sessions, and their brain waves were measured before and after.…

This study used brain imaging and memory tests to find early signs of Alzheimer's disease. Researchers followed 242 volunteers, including healthy young, middle-aged, and older adults, to track changes over time. The goal was to understand how the disease develops and identify mar…

This study tested a new breathing machine mode called NAVA in 15 patients recovering from acute lung injury. The goal was to see how their bodies responded to different levels of support from the machine. The study did not aim to treat or cure the lung injury, but to gather infor…

This study tested a new device called E-Celsius, which is a pill you swallow that measures your body temperature as it travels through your digestive tract. Researchers compared its readings to standard thermometers placed in the rectum or esophagus in 22 healthy volunteers. The …

This study placed 15 healthy volunteers in a natural cave with no access to time cues for 40 days. Researchers measured how their sense of time, sleep cycles, stress levels, and group coordination changed. The goal was to understand how humans adapt to extreme isolation and time …

This study tested whether giving 50% or 100% oxygen before removing a breathing tube after anesthesia leads to fewer drops in oxygen levels. 119 patients were monitored after surgery. The goal is to find the safest oxygen setting to prevent breathing problems during recovery.

This study looked at how psychological trauma affects memory and brain function in teenagers with post-traumatic stress disorder (PTSD). Researchers used MRI scans to compare brain activity in 19 adolescents with PTSD and healthy teens. The goal was to understand the brain areas …

This study looks at how a single 5 mg dose of the blood thinner apixaban is processed in people with end-stage kidney disease who are on peritoneal dialysis, compared to people with normal kidney function. Researchers measured drug levels in the blood over time. The goal is to un…

This study tested whether a non-invasive imaging technique can measure tiny blood vessels (microcirculation) during brief weightlessness on parabolic flights. Sixteen healthy volunteers were observed during 21-second periods of zero gravity. The goal was to understand how the car…

This study tested whether pregnant women can have their pre-birth anesthesia consultation through a video call instead of coming to the hospital. 60 women participated, using a telemedicine cabin or cart near their home. The goal was to see if the video assessment of the airway i…

This study looked at how compression therapy changes oxygen levels in the skin of people with leg ulcers that involve both arteries and veins. Researchers measured oxygen before and during compression in 38 adults. The goal was to better understand how compression works and how w…

This study tested a French version of a questionnaire that measures physical activity levels in people with physical disabilities. Fifty participants with conditions like stroke, multiple sclerosis, or Parkinson's disease filled out the questionnaire twice, two weeks apart. The g…

This study tested whether a half-day simulation-based training session helps pediatric residents perform better heart ultrasounds on newborns. Fifty-two residents from three French hospitals were randomly assigned to receive either simulation training plus usual training or usual…

This study compared traditional pencil-and-paper tests with virtual reality tasks (like driving simulations and a virtual supermarket) to assess attention and executive function in 60 people with relapsing-remitting multiple sclerosis. The goal was to see if VR can better detect …

This study looked at how brief periods of weightlessness during parabolic flights (like those used to train astronauts) affect the brain's memory and navigation centers. Twenty-four healthy volunteers underwent brain scans and cognitive tests before and after flying. The goal was…

This study looked at 206 medical residents in France to see if their physical activity levels are linked to anxiety, depression, and burnout. Participants filled out online surveys about their exercise habits and mental health. The goal is to understand whether staying active mig…

This study explores whether a single general anesthesia before age 4 can affect thinking skills like memory, attention, and flexibility in children aged 9-10. Researchers compared 80 children—half had anesthesia, half did not—using computer tasks. The goal is to understand if ear…

This study looked at reports from the WHO global safety database to see if common heart failure medications are linked to falls in people aged 65 and older. Researchers analyzed over 100,000 records to find which drugs were most often associated with fall reports. The goal is to …