Can baking soda protect ICU Patients' kidneys from dye damage?

NCT ID NCT01636089

Completed Prevention Sponsor: University Hospital, Caen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a bicarbonate solution (like baking soda) is better than standard saline for preventing kidney injury caused by contrast dye used in imaging. The trial involved 300 adults in intensive care who needed contrast dye. Researchers compared how many patients in each group developed acute kidney injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sodium bicarbonate (1.4% solution)
What this could lead to: If bicarbonates work better than saline, this could give ICU doctors a simple, cheap way to prevent kidney damage from contrast dyes.
What could go wrong: This is a completed Phase 3 trial, but results may not apply to all ICU patients. Bicarbonates can cause side effects like electrolyte imbalances.

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Conditions

The condition(s) this trial relates to.

acute kidney injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONTRAST INDUCED ACUTE KIDNEY INJURY

Contacts and locations

Locations

Intensive care unit

Saint-Lô, 50000, France
Medical Intensive Care Unit

Caen, 14033, France
Surgical Intensive Care Unit

Caen, 14033, France

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