University Hospital, Caen

This study will test a new type of defibrillator lead designed to pace a specific area of the heart's electrical system. Researchers want to see if these leads can effectively treat heart failure while possibly reducing the number of leads needed. The study plans to enroll 200 pe…

This study explores whether general practitioners can use a tiny ultrasound device to detect early signs of heart disease during a routine office visit. Researchers will enroll 300 adults aged 65 and older with risk factors, or adults with symptoms like shortness of breath or leg…

This study compares a new emollient balm made from seawater (Relipid+) to a leading balm (Lipikar) for mild to moderate eczema in people aged 6 months to 70 years. The goal is to see if the new balm works just as well at reducing symptoms and improving skin health. Researchers wi…

This study compares two ways to numb the area for pain relief after circumcision in children: an ultrasound-guided penile block and a nerve-stimulation-guided pudendal block. Researchers want to see if the ultrasound method works just as well. About 240 children will take part to…

This study tests whether listening to music at home can improve the quality of life and reduce burnout in people caring for a loved one with Alzheimer's. Ninety caregiver-patient pairs will be split into groups, with some listening to music or podcasts three times a week for 12 w…

This study will collect data from up to 10,000 cancer patients across Europe to create better tools for predicting heart damage caused by certain cancer treatments. Researchers will use artificial intelligence alongside standard methods to develop risk scores that doctors can use…

This study tests whether sending an early letter with information about colonoscopy—either from the screening center alone or co-signed by the patient's own doctor—can increase the number of people who get a follow-up colonoscopy within 6 months of a positive colorectal cancer sc…

This study will follow 120 adults receiving a stem cell transplant to see if the types of viruses and bacteria in their lungs can predict future lung complications. Researchers will collect samples from the nose and lungs over time and analyze them using advanced genetic techniqu…

This study will find the correct dose of sugammadex, a drug that reverses muscle relaxants, for infants under 2 years old. About 99 babies having non-emergency surgery will receive small, increasing doses until their muscle function returns. The goal is to ensure safe and complet…

This study tests a new way to place a pacemaker lead in the heart's upper chambers. The goal is to see if pacing a specific area (Bachmann's bundle) can keep the heartbeat more natural and reduce the risk of atrial fibrillation. About 200 adults who need a pacemaker will take par…

This study follows 270 preterm babies (born before 32 weeks) from birth to age 3. Researchers will regularly swab their noses to analyze the bacteria and other microbes living there. The goal is to see if the nose microbiome can predict which babies will develop bronchopulmonary …

This study looks at how treatment failure impacts the quality of life, anxiety, depression, and daily activities of 150 adults with relapsing-remitting multiple sclerosis. Researchers will use questionnaires to measure patients' well-being and their experience with care. The goal…

This study looks at medical records of 15,000 adults with chronic B-cell cancers to compare the risk of developing atrial fibrillation (an irregular heartbeat) between two drugs, zanubrutinib and acalabrutinib. Researchers will analyze data from a health database to see which dru…