Tiny noses, big clues: study hopes nose bugs predict preterm lung disease

NCT ID NCT07411261

Not yet recruiting Knowledge-focused Sponsor: University Hospital, Caen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 270 preterm babies (born before 32 weeks) from birth to age 3. Researchers will regularly swab their noses to analyze the bacteria and other microbes living there. The goal is to see if the nose microbiome can predict which babies will develop bronchopulmonary dysplasia (a chronic lung disease) or later asthma and infections. This is an observational study, meaning no new treatment is being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a way to predict which preterm babies are at risk for lung problems, allowing for earlier monitoring or treatment.
What could go wrong: This is an observational study, not a treatment trial. It may not find a clear link between the microbiome and lung disease, or the results may not apply to all preterm infants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma bronchiolitis bronchopulmonary dysplasia childhood onset asthma Dysbiosis Inflammation Premature Birth respiratory tract infectious disorder viral respiratory tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA CHILDHOOD BRONCHIOLITIS BRONCHOPULMONARY DYSPLASIA PRETERM INFANT DEVELOPMENT VIRAL RESPIRATORY TRACT INFECTIONS

Contacts and locations

Locations

Service de néonatalogie, CH Cherbourg-en-Cotentin

Cherbourg, 50000, France
Service de néonatalogie, CHRU de Lille

Lille, 59000, France
Service de néonatalogie, CHU d'Amiens

Amiens, 80000, France
Service de néonatalogie, CHU de Caen

Caen, 14000, France
Service de néonatalogie, CHU de Rouen

Rouen, 76000, France
Service de néonatalogie, GHT du Havre

Le Havre, 76600, France

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