Could a liver cancer drug slow eye cancer spread?

NCT ID NCT02517736

First seen Feb 18, 2026 · Last updated Jun 22, 2026 · Updated 22 times

Summary

This study tested the drug sorafenib (Nexavar) in 32 adults with uveal melanoma that had spread to other parts of the body. The goal was to see if the drug could stop tumors from growing for at least 24 weeks. Sorafenib is already used for other cancers, and researchers wanted to know if it could help control this rare eye cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Service d'ophtalmologie, CHU de Caen

    Caen, 14000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sorafenib (Nexavar)

What this could lead to

If successful, sorafenib could offer a treatment option to slow tumor growth in patients with metastatic uveal melanoma.

What could go wrong

This is a small Phase 2 trial with only 32 participants, so results may not apply broadly. Sorafenib can cause side effects like fatigue, diarrhea, and skin reactions.

Conditions

The condition(s) this trial relates to.

uveal melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.