The Cleveland Clinic

This study followed 30 people with uveitis (eye inflammation) who received a fluocinolone acetonide implant. Researchers used special eye scans to measure inflammation changes over 12 months. The goal was to see how the implant affects inflammation and vision, not to test a new t…

This study tested whether yoga can help African American adults with high blood pressure manage stress, remember to take their medication, and lower their blood pressure. Eight participants attended weekly yoga classes for 8 weeks. Researchers measured blood pressure, stress leve…

This study compared two types of surgical mesh used to repair vaginal vault prolapse, a condition where the top of the vagina drops down. 106 women having laparoscopic or robotic surgery were randomly assigned to receive either Restorelle® Y mesh or Vertessa® Lite Y mesh. The mai…

This study looked at whether a program that combines WeightWatchers behavioral coaching with prescription weight-loss drugs (Wegovy, Mounjaro, or Zepbound) helps people lose weight. 180 adults with obesity or weight-related health issues took part for 24 weeks. Researchers measur…

This study tested how well a wearable thermometer called TempTraq measures body temperature compared to the standard method (a tube in the heart) in 60 ICU adults. The goal was to see if the patch is accurate and reliable for patients who are cold, normal, or feverish. Results he…

This study looked at whether the aldosterone renin ratio (ARR) test can help doctors find more cases of primary aldosteronism (PA), a common and often missed cause of high blood pressure that can be cured with surgery or treated with specific medications. Researchers tested 53 ad…

This study tested whether a gentle, non-invasive brain stimulation technique could improve arm and hand function in people with cervical spinal cord injury. 47 participants completed 15 sessions of arm training combined with brain stimulation over several weeks. Researchers measu…

This study tested a cooling spray (vapocoolant) to see if it reduces pain when placing an IV in emergency department patients. 300 adults who needed an IV were randomly given either the cooling spray or sterile water before the needle. The main goal was to measure pain scores usi…

This study tested a group-based program to help people with moderate-to-severe sleep apnea use their Positive Airway Pressure (PAP) machine more consistently. Fifty-six adults who were new to PAP therapy and struggling to use it enough took part. The program aimed to improve mach…

This study tested whether ketorolac (an NSAID painkiller) works as well as oxycodone (an opioid) for managing pain after kidney stone removal. 81 adults who had ureteroscopy and received a ureteral stent took part. For five days after surgery, they recorded their pain levels, how…

This small study tested whether acupuncture could improve heart function and quality of life in 14 people with chronic heart failure. Participants received acupuncture treatments over 5 weeks, and researchers measured changes in heart pumping ability, walking distance, and sympto…

This study compared two surgical methods for removing kidney stones: standard PCNL and a smaller version called mini-PCNL. Researchers wanted to see which one causes less blood loss and leads to a quicker hospital discharge. The trial included 18 adults with stones between 10-20m…

This study looked at whether adding Reiki (a light-touch energy therapy) and manual therapy (gentle massage) to standard care helps people who just had open-heart surgery. 272 adults were randomly assigned to receive either these therapies or rest. The goal was to see if the ther…

This study tested whether radiofrequency microneedling (RFMN) can safely treat melasma, a condition causing dark patches on the face, in people with darker skin (Fitzpatrick types IV-VI). Ten adults completed the treatment, and researchers measured changes in melasma severity usi…

This study tested whether numbing chest muscles (PECS/SAP blocks) with a long-lasting anesthetic improves pain control after minimally invasive heart surgery. 210 adults having robot-assisted mitral valve repair took part. The main goal was to see if the blocks reduced a combined…

This study looked at how pain in one knee affects the forces on the other knee during walking. Researchers studied 55 people with knee osteoarthritis and healthy volunteers. Participants walked on a treadmill and received knee injections to help measure changes. The goal was to u…

This study looked at side effects of oliceridine, a pain medicine, in 204 adults after major surgery. Researchers measured breathing problems like low oxygen or slow breathing. The goal was to understand how safe this drug is for patients needing strong pain relief.

This study looked at how a single session of exercise changes brain activity in 25 people with Parkinson's disease who have a deep brain stimulation (DBS) device. Participants did both fast and voluntary cycling while off their usual medications and DBS. The goal was to understan…

This study looked at whether using a continuous monitoring system (GE Portrait) with nurse alerts can reduce dangerous changes in vital signs like low oxygen, abnormal breathing, and heart rate issues in adults recovering from major noncardiac surgery. Over 200 participants were …

This study tested whether a special imaging technique called near infrared fluorescence cholangiography (NIFC) helps surgeons see bile ducts more clearly during laparoscopic gallbladder removal compared to standard white light. 677 adults having gallbladder surgery took part. The…

This study tested whether a continuous glucose monitor (CGM) can help track blood sugar changes in 20 adults with type 2 diabetes after a kidney transplant. Participants wore the CGM for a short time to measure how often their glucose stayed in a safe range. The goal was to learn…

This study compared two advanced heart-mapping systems, RHYTHMIA and CARTO, in 49 adults undergoing a repeat procedure (redo ablation) for paroxysmal atrial fibrillation. The main goal was to see how accurately each system could identify gaps from previous ablation lines. Researc…

This study looked at whether stopping certain diabetes medications (incretin-based therapies) before an upper endoscopy lowers the chance of having leftover food or liquid in the stomach that could interfere with the procedure or cause complications. 69 adults with type 2 diabete…

This study looked at how choline from eggs or supplements changes levels of TMAO, a compound tied to higher heart disease risk. Researchers compared 86 adults who ate eggs or took choline pills for 28 days. The goal was to see if the source of choline matters for TMAO production …

This study observed how doctors discuss noninvasive prenatal testing (NIPT) with pregnant women during their first prenatal visit. The goal was to understand current practices and find ways to help women make informed decisions about whether to use this screening test. Over 600 p…

This study followed 37 people who carry a genetic mutation for hereditary ATTR amyloidosis but do not yet have symptoms. Over five years, researchers measured a specific misfolded protein in the blood to see if it changes when the disease starts or when treatment is needed. The g…

This study looked at 70 premature babies in the NICU to see if levels of certain proteins (neurotrophins) in their blood could predict later breathing problems and developmental delays. Researchers measured these proteins over time and checked how the babies' lungs and brains dev…

This study looked at 16 people having weight-loss surgery to see how raising pressure in the belly (like in a condition called abdominal compartment syndrome) affects a hormone called vasopressin and kidney function. Researchers measured pressure, hormone levels, and urine output…

This study looked at 64 people hospitalized for acute heart failure to see if a blood marker called cystatin C could predict kidney problems caused by diuretic (water pill) treatment. Researchers measured cystatin C levels daily and compared them to standard kidney tests. The goa…

This study involved 15 people with Parkinson's disease who had a deep brain stimulator (DBS) implanted. They walked through a virtual reality environment designed to trigger freezing of gait while their brain signals were recorded. The goal was to better understand what happens i…

This study tested how well different warming blankets and devices prevent heat loss in 20 healthy adults. Researchers measured heat transfer at 15 spots on the body and asked volunteers how warm they felt. The goal was to understand which systems work best, not to treat any disea…

This study tested new ways of delivering deep brain stimulation (DBS) to people with Parkinson's disease. The goal was to see if intermittent stimulation patterns could control movement symptoms as well as standard continuous stimulation, but with fewer effects on thinking and me…

This study looked at how well the Dexcom G6 continuous glucose monitor matches standard blood sugar checks in 40 adults after heart surgery. Participants wore the monitor while in the intensive care unit and on regular hospital floors. The goal was to see if the device could reli…

This study looked at how well the Dexcom G7 continuous glucose monitor agrees with usual blood sugar checks in 28 adults after heart surgery. Participants had their blood sugar measured every 1-3 hours using standard methods, and the Dexcom G7 readings were recorded at the same t…

This study tested a telemedicine approach to deliver cervical cancer screening results to women in El Salvador. Over 1,100 women aged 30 to 59 took part, and researchers measured how many received their results within 45 days. The goal was to see if using mobile phones could impr…

This early study tested a 3D holographic system to help guide doctors during a procedure to repair an abdominal aortic aneurysm (a bulging blood vessel). Two patients participated, and the system was used alongside standard X-ray imaging to place a stent graft. The goal was to se…

This study looked at whether people with a higher body weight and a higher risk for sleep apnea are more likely to have breathing or heart problems during an endoscopy. About 350 adults having an upper endoscopy or colonoscopy took part. Researchers used simple questionnaires to …