The Cleveland Clinic
Clinical trials sponsored by The Cleveland Clinic, explained in plain language.
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New tech approach aims to prevent repeat diabetes emergencies
Disease control TerminatedThis study tested whether a special care program using continuous glucose monitors and a team of diabetes experts could help adults with type 1 diabetes better control their blood sugar after a serious complication called diabetic ketoacidosis (DKA). The goal was to see if this a…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated May 17, 2026 00:52 UTC
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Stem cell shot for gut disease shows early promise
Disease control TerminatedThis study tested a stem cell product called Remestemcel-L in 7 adults with severe ulcerative colitis that did not respond to standard treatments. The goal was to see if injecting these cells into the colon could reduce inflammation and help patients avoid surgery. The trial was …
Phase: PHASE1, PHASE2 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Stem cells injected into colon aim to tame tough Crohn's
Disease control TerminatedThis study tested a new way to treat severe Crohn's colitis that hasn't responded to standard medicines. Doctors injected stem cells directly into the inflamed colon to see if it was safe and could help patients avoid surgery. The study was small and stopped early, so results are…
Phase: PHASE1, PHASE2 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Crohn's surgery showdown: which technique wins?
Disease control TerminatedThis study compared two surgical methods for removing diseased intestine in people with Crohn's disease to see which better prevents the disease from returning. It involved 13 adults who needed surgery for Crohn's that didn't respond to medication. The trial was stopped early, so…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Which seton material works best for anal fistulas? study aims to find out
Symptom relief TerminatedThis study compared two types of seton (a drainage thread) used for complex anal fistulas: Ethibond suture and vessel loop. The goal was to see which material drains infection better, lasts longer without breaking, and improves quality of life. The study planned to include adults…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated May 17, 2026 00:50 UTC
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Septic shock study seeks to uncover hidden patient subtypes
Knowledge-focused TerminatedThis observational study aimed to understand why some people with septic shock respond better to the drug vasopressin than others. Researchers planned to compare blood markers, heart ultrasound images, and tissue oxygen levels between responders and non-responders. Only 2 partici…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 00:53 UTC
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Hernia surgery pressure study stopped early
Knowledge-focused TerminatedThis study looked at how fixing large hernias in the belly wall changes the tension and pressure inside the abdomen. Researchers planned to measure these changes in adults having open surgery with mesh. Only 2 people took part before the study was stopped.
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC
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Can shedding pounds slow aging at the cellular level?
Knowledge-focused TerminatedThis study looked at whether weight-loss surgery can lengthen telomeres, which are caps on our DNA that shorten as we age. Researchers compared telomere length in people with severe obesity before and after surgery. The goal was to see if rapid weight loss might reverse some sign…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 04, 2026 16:22 UTC