Crohn's surgery showdown: which technique wins?
NCT ID NCT04578392
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two surgical methods for removing diseased intestine in people with Crohn's disease: one that cuts the main artery high up, and one that spares the mesentery (the tissue holding the intestine). The goal was to see which technique better prevents the disease from coming back within 6 months. Only 13 adults with limited Crohn's disease took part before the study was stopped early.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
surgical procedure (high ligation vs. mesenteric sparing ileocolic resection)
What this could lead to
If successful, this could help identify a better surgical approach to reduce the chance of Crohn's disease returning after surgery.
What could go wrong
The trial was terminated early with very few participants (13), so results are limited and may not be reliable. It is unclear if either technique is truly better.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cedars-Sinai Hospital System
Los Angeles, California, 90048, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Cleveland Clinic Florida
Weston, Florida, 33331, United States
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Humanitas
Rozzano, Milano, 20089, Italy
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Mt. Sinai
Toronto, Ontario, M5G 1X5, Canada
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St Mark's Hospital and Academic Institution
Harrow, Middlesex, HA1 3UJ, United Kingdom
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Stanford University School of Medicine
Stanford, California, 94305, United States