Could a common NSAID replace opioids for kidney stone surgery pain?

NCT ID NCT03888144

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether ketorolac, a non-steroidal anti-inflammatory drug (NSAID), works as well as the opioid oxycodone for pain after kidney stone removal. 81 adults who had ureteroscopy and received a ureteral stent took part. For five days after surgery, they recorded their pain levels and how much medication they used. The goal was to see if ketorolac could provide similar pain relief with fewer opioid-related side effects.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis Ureteral Calculi ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States