Smaller tube, same stone removal: new kidney stone surgery tested

NCT ID NCT05088213

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial compares two surgical techniques for removing kidney stones that are 2 to 4 centimeters in size. The newer method, called suction mini-PCNL, uses a smaller tube and suction to remove stone fragments, while the standard method uses a larger tube. The goal is to see if the newer method works just as well at clearing stones while causing fewer complications like bleeding and infection. The study involves 960 adults aged 18 to 70 across multiple international centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
suction mini percutaneous nephrolithotomy (mini-PCNL) procedure
What this could lead to
If successful, this could offer a safer, less invasive surgical option for removing medium-to-large kidney stones, with less bleeding and shorter hospital stays.
What could go wrong
This is a noninferiority trial, meaning it aims to show the new method is not worse than the standard. It may still have higher infection risk or longer surgery time.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Urology, Minimally invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University

    Guangzhou, Guangdong, 510230, China

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