Medical College Of Wisconsin
Clinical trials sponsored by Medical College Of Wisconsin, explained in plain language.
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Friendship as medicine: can peer groups help control HIV?
Disease control CompletedThis study tested whether group sessions for friends who all have HIV could help them stay in medical care and take their medication consistently. Researchers in Russia worked with 341 people living with HIV, organizing them into friend networks. They compared group support sessi…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Engineered immune cells tested to fight stubborn blood cancer
Disease control CompletedThis study tested a personalized cell therapy for adults with multiple myeloma, a blood cancer. It was for patients whose cancer did not respond well enough to a prior stem cell transplant and standard maintenance drug. Doctors collected and re-engineered the patients' own immune…
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Ancient herbs target oral cancer in groundbreaking trial
Disease control CompletedThis early-stage study tested whether a traditional Chinese herbal formula called Anti-tumor B could slow the growth of oral cancer cells. Thirty adults with oral cancer scheduled for surgery took the herbal pills for 7 to 28 days before their operation. Researchers compared tumo…
Phase: EARLY_PHASE1 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Gut bacteria linked to heart attack severity; probiotic tested as potential shield
Disease control CompletedThis study tested whether a daily probiotic supplement could improve blood vessel function and reduce markers of inflammation in people with coronary artery disease or type 2 diabetes. Researchers enrolled 215 participants to see if changing gut bacteria could help control heart …
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Psoriasis drug shows promise in preventing deadly transplant complication
Disease control CompletedThis study tested whether tildrakizumab, a drug approved for psoriasis, could prevent graft-versus-host disease (GVHD) in patients receiving stem cell transplants for blood cancers. The trial involved 51 adults who received the drug alongside their transplant to see if it could r…
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Three-Pronged attack tested against Tough-to-Treat uterine cancer
Disease control CompletedThis study tested a combination of three existing drugs—bevacizumab, atezolizumab, and rucaparib—to see if they could work together to control recurrent or progressive endometrial cancer. It involved 30 patients whose cancer had returned or worsened after prior chemotherapy. The …
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Cancer treatment in one week? study tests faster radiation
Disease control CompletedThis study aimed to find out if a much shorter course of radiation therapy could be safely given after surgery for head and neck cancer. It tested reducing treatment from the standard six weeks down to just one week for 18 patients. The main goal was to check if the shorter treat…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Can tackling food and housing needs improve health for diabetic kidney patients?
Disease control CompletedThis study tested whether a support program could help low-income African Americans with diabetic kidney disease who face challenges like food or housing insecurity. Fifty participants were randomly assigned to receive either the full program—which included education, help meetin…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Doctors flip the script: zapping brain tumors *Before* cutting them out
Disease control CompletedThis small pilot study tested a new order of treatment for patients with 1 to 4 brain tumors that have spread from other cancers. Instead of the usual surgery followed by radiation, researchers gave a precise, high-dose radiation treatment first, then performed surgery within 10 …
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Faster radiation tested to fight tough tumors
Disease control CompletedThis study tested a shorter, more intense schedule of radiation therapy given before surgery for soft tissue sarcomas in the arms, legs, or chest wall. The goal was to see if this approach could control the cancer as well as standard, longer radiation while being more convenient …
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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New transplant prep shows promise for older, sicker blood cancer patients
Disease control CompletedThis study tested a new, potentially safer drug combination to prepare patients for a half-matched bone marrow transplant. It involved 43 adults with blood cancers like multiple myeloma who could not tolerate standard high-dose treatments. The goal was to see if this gentler prep…
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Mar 09, 2026 14:24 UTC
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Scientists test deeper swab for better anal cancer detection
Diagnosis CompletedThis study tested a new self-swab tool to see if inserting it deeper (5 cm vs. 3 cm) collects better cell samples for anal cancer screening. Researchers wanted to find the best method to collect cells from a specific area prone to cancer, while also checking if the deeper swab wa…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Diagnosis
Last updated Mar 16, 2026 15:25 UTC
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Freezing nerves to fight surgery pain and opioid use
Symptom relief CompletedThis study tested whether freezing nerves during robotic lung surgery helps reduce pain afterward. Researchers compared the new freezing technique to standard pain care in 33 patients. The goal was to see if it lowered pain scores and reduced the need for opioid painkillers durin…
Phase: PHASE4 • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Zapping the brain to boost memory: early trial tests new approach
Symptom relief CompletedThis small pilot study tested whether a combination of gentle, non-invasive brain stimulation and computer-based memory training was a practical approach for people with mild cognitive impairment (MCI). Eight participants aged 50-90 with early memory loss completed the study. The…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Zap to the brain may help stroke patients talk again
Symptom relief CompletedThis study tested whether adding mild electrical brain stimulation to standard speech therapy helps people with long-term speech problems after a stroke. Twenty-five adults with chronic aphasia received either real or sham stimulation during therapy sessions while their brains we…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Could a tiny ear device calm teen stomach woes?
Symptom relief CompletedThis study tested whether a small, non-invasive stimulator placed on the outer ear could reduce nausea in teenagers with functional gastrointestinal disorders. 109 teens participated, with half receiving an active device and half receiving a fake one for comparison over four week…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Mar 30, 2026 14:27 UTC
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New nerve block combo could ease heart surgery recovery
Symptom relief CompletedThis study tested whether adding a second type of nerve block to a standard pain control method improves recovery after heart surgery. Researchers compared pain levels, opioid medication use, and breathing function in 62 patients who received either one or two types of nerve bloc…
Phase: PHASE1 • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Ear zapper tested to stop debilitating vomiting episodes
Symptom relief CompletedThis small pilot study tested whether a non-invasive device that stimulates nerves in the ear could help people with cyclic vomiting syndrome (CVS). CVS causes severe, recurring episodes of nausea, vomiting, and pain. Researchers compared the effects of the real stimulator to a f…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Mar 16, 2026 15:24 UTC
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Sweetener study probes hidden health effects in diabetic youth
Knowledge-focused CompletedThis study aimed to understand how non-caloric artificial sweeteners might affect the health of young people with type 1 diabetes. Researchers measured body fat, muscle, and blood markers in 21 youth to see if sweetener use was linked to changes in weight, blood sugar control, or…
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Can a simple texted video transform tough pregnancy conversations?
Knowledge-focused CompletedThis study tested whether sending an animated video by text message helps parents prepare for difficult conversations with doctors when their pregnancy involves a fetal anomaly. Researchers compared 48 parents who received the video to those who got standard webpage links, measur…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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AI steps into the operating room as a teaching assistant for anesthesia trainees
Knowledge-focused CompletedThis study tested whether a new artificial intelligence (AI) tool could help teach anesthesia residents how to perform ultrasound-guided nerve blocks. Twenty residents with no prior experience used the AI device during training. Researchers wanted to see if the AI made the teachi…
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Researchers track Mothers' recovery from rare Post-Birth heart crisis
Knowledge-focused CompletedThis study aimed to understand the long-term recovery of women who developed a rare, severe form of heart failure (peripartum cardiomyopathy) with life-threatening shock after childbirth. Researchers observed 10 women to compare the outcomes of those who were treated with a speci…
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Listening to the ear during surgery: can a new tool improve cochlear implant results?
Knowledge-focused CompletedThis study tested if giving surgeons real-time feedback about the inner ear's response to sound during cochlear implant surgery leads to better outcomes. It involved 88 people getting a cochlear implant, who were randomly assigned to have the feedback system on or off during thei…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC