Fewer radiation sessions may be safe for head and neck cancer patients

NCT ID NCT05120947

Completed Disease control Sponsor: Medical College of Wisconsin Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving fewer, higher-dose radiation sessions after surgery for head and neck cancer is safe. Eighteen adults with certain risk factors received one of three shortened radiation schedules. The goal was to find the shortest course that does not cause severe side effects within a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (hypofractionated)
What this could lead to: If successful, this could lead to shorter, more convenient radiation treatment after surgery for head and neck cancer, reducing the number of hospital visits.
What could go wrong: This is a very small, early-phase study with only 18 participants, so results may not apply to everyone. Higher radiation doses per session could increase side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RESECTABLE HEAD AND NECK SQUAMOUS-CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESECTABLE HEAD AND NECK SQUAMOUS-CELL CARCINOMA

Contacts and locations

Locations

Froedtert & the Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.