New transplant method shows promise for rare blood disorder

NCT ID NCT02918292

First seen Apr 05, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study tested a new way to do stem cell transplants for people with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. The approach used a half-matched donor (haploidentical) to help more patients find a donor. The main goal was to see how many patients were alive one year after the transplant.

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Contacts and locations

Locations

  • All Children's Hospital

    St. Petersburg, Florida, 33701, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Children's Hospital and Research Center Oakland

    Oakland, California, 94618, United States

  • Children's Hospital of Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Wisconsin/Midwest Children's Cancer

    Milwaukee, Wisconsin, 53211, United States

  • Children's Mercy Hospital and Clinics

    Kansas City, Missouri, 64108, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Duke University Medical Center

    Durham, North Carolina, 27705, United States

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington, 98109, United States

  • H. Lee Moffitt Cancer Center

    Tampa, Florida, 33624, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Indiana University Medical Center/ Riley Hospital for Children

    Indianapolis, Indiana, 46202, United States

  • Johns Hopkins Unversity

    Baltimore, Maryland, 21231, United States

  • Karmanos Cancer Institute/Children's Hospital of Michigan

    Detroit, Michigan, 48201, United States

  • Miami Children's Hospital

    Miami, Florida, 33155, United States

  • Northside Hospital

    Atlanta, Georgia, 30342, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239-3098, United States

  • Penn State College of Medicine/The Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Stanford Hospital and Clinics

    Stanford, California, 94305, United States

  • Texas Transplant Institute

    San Antonio, Texas, 78229, United States

  • University of Florida College of Medicine

    Gainesville, Florida, 32610, United States

  • University of Louisville/Kosair Children's Hospital

    Louisville, Kentucky, 40202, United States

  • University of Michigan Medical Center

    Ann Arbor, Michigan, 48105, United States

  • University of Pennsylvania Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas/MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Washington University/Barnes Jewish Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.