New melphalan combo shows promise in Half-Matched transplants for blood cancer patients
NCT ID NCT03159702
First seen Feb 01, 2026 · Last updated Jun 12, 2026 · Updated 24 times
Summary
This study tested a new version of the chemotherapy drug melphalan (EVOMELA) combined with fludarabine and total body irradiation before a half-matched (haploidentical) stem cell transplant in 43 adults with blood cancers like multiple myeloma. The goal was to see if this approach is safe and helps patients live longer without their cancer getting worse. Results showed the treatment was generally safe, with serious side effects monitored, and one-year progression-free survival was evaluated.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Froedtert Hospital & the Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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