New drug shows promise in preventing transplant complications for blood cancer patients

NCT ID NCT04112810

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 36 times

Summary

This study tested whether the drug tildrakizumab can help prevent graft-versus-host disease (GVHD) in people receiving a stem cell transplant for blood cancers. GVHD occurs when donor cells attack the patient's body. The trial included 51 adults with blood cancers like leukemia. Researchers measured how many patients remained free of severe GVHD, relapse, or death one year after transplant.

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Contacts and locations

Locations

  • Froedtert Hospital and the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

Conditions

Explore the condition pages connected to this study.