Medical College Of Wisconsin

This study tested a combination of chemotherapy drugs (cladribine, cytarabine, mitoxantrone, and G-CSF) in 53 adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) that had come back or not responded to prior treatment. The goal was to see how many …

This early-phase study tested a personalized cell therapy (CAR-T) for people with B-cell acute lymphoblastic leukemia that returned or didn't respond to standard treatments. The therapy used the patient's own immune cells, modified to target two markers (CD19 and CD20) on leukemi…

This phase 2 trial tested the drug pacritinib in 6 men whose prostate cancer had come back after surgery or radiation, shown by rising PSA levels. The goal was to see if the drug could delay further cancer growth. However, the study was terminated early, so we have limited inform…

This early-phase trial tested a drug called CPI-613 (devimistat) combined with chemotherapy and radiation for people with pancreatic cancer that cannot be surgically removed. The goal was to find the safest dose. Only 8 people took part before the study was stopped. While the app…

This study tested a small device placed on the ear that sends gentle electrical pulses to calm overactive nerves in children with severe brain injury. The goal was to reduce sudden episodes of fast heart rate, high blood pressure, and other symptoms. The trial was very small and …

This study tested a small device that stimulates nerves in the ear to help people with cyclic vomiting syndrome feel less pain, nausea, and vomiting. The goal was to see if it could reduce the need for strong painkillers like opioids. Only 4 people took part before the study was …

This study tested a small device that stimulates a nerve in the ear to see if it can reduce nausea and vomiting caused by chemotherapy in children, teens, and young adults. The device, called IBStim, was compared to a sham (fake) device. The trial was terminated early and include…