Medical College Of Wisconsin

This pilot study tests whether a special PET scan tracer called 18F florbetapir can detect changes in amyloid protein deposits in the heart of people with AL cardiac amyloidosis who are receiving chemotherapy. Four participants will have a PET/CT scan before starting chemotherapy…

This study tested a combination of chemotherapy drugs (cladribine, cytarabine, mitoxantrone, and G-CSF) in 53 adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) that had come back or not responded to prior treatment. The goal was to see how many …

This early-phase study tested a personalized cell therapy (CAR-T) for people with B-cell acute lymphoblastic leukemia that returned or didn't respond to standard treatments. The therapy used the patient's own immune cells, modified to target two markers (CD19 and CD20) on leukemi…

This phase 2 trial tested the drug pacritinib in 6 men whose prostate cancer had come back after surgery or radiation, shown by rising PSA levels. The goal was to see if the drug could delay further cancer growth. However, the study was terminated early, so we have limited inform…

This early-phase trial tested a drug called CPI-613 (devimistat) combined with chemotherapy and radiation for people with pancreatic cancer that cannot be surgically removed. The goal was to find the safest dose. Only 8 people took part before the study was stopped. While the app…

This study is testing whether a simple ultrasound done right in the doctor's office can help diagnose fatty liver disease early. Researchers will compare the bedside scan results with standard radiology imaging in 500 patients. If it works, it could make diagnosis faster and more…

This trial investigates whether lidocaine patches can help older adults (65+) with rib fractures use fewer opioids while maintaining pain control. Participants receive either a lidocaine patch, a placebo patch, or standard care. The study measures opioid use and pain scores durin…

This study tested a small device placed on the ear that sends gentle electrical pulses to calm overactive nerves in children with severe brain injury. The goal was to reduce sudden episodes of fast heart rate, high blood pressure, and other symptoms. The trial was very small and …

This study tested a small device that stimulates nerves in the ear to help people with cyclic vomiting syndrome feel less pain, nausea, and vomiting. The goal was to see if it could reduce the need for strong painkillers like opioids. Only 4 people took part before the study was …

This study tested a small device that stimulates a nerve in the ear to see if it can reduce nausea and vomiting caused by chemotherapy in children, teens, and young adults. The device, called IBStim, was compared to a sham (fake) device. The trial was terminated early and include…

This study watches hospitalized infants who receive long-term tube feedings to see how their behaviors around feeding change over time. Researchers compare these infants to those fed orally, looking for early clues that might predict oral feeding difficulty later in life. The goa…