Experimental Dual-Target CAR-T therapy for tough leukemia shows early promise but study halted

NCT ID NCT04049383

First seen Jan 12, 2026 · Last updated May 05, 2026 · Updated 16 times

Summary

This early-stage study tested a personalized cell therapy (CAR-T) that targets two markers (CD19 and CD20) on leukemia cells. It included 5 patients with B-cell acute lymphoblastic leukemia that had returned or not responded to standard treatments. The main goal was to check safety and side effects. The study was terminated early, so full results are limited.

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Contacts and locations

Locations

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

Conditions

Explore the condition pages connected to this study.