TOTAL KNEE ARTHROPLASTY

This study tests whether whole-body vibration therapy, alone or combined with exercise, can improve bone health and physical function in women with low bone density who have had a total knee replacement. Forty-eight women will be randomly assigned to vibration only, vibration plu…

This study looked at whether a special vacuum dressing (negative pressure wound therapy) can reduce surgical site infections in high-risk patients undergoing revision hip or knee replacement. 104 patients were enrolled. The goal was to see if this approach lowers complication rat…

This study tested three different nerve blocks to see which provides the best pain relief after total knee replacement. Sixty adults having knee surgery under general anesthesia received one of the blocks. The main goal was to measure how long it took before they needed extra pai…

This study tested whether giving lidocaine through an IV works as well as an ultrasound-guided nerve block for controlling pain after total knee replacement. 120 adults having knee surgery were randomly assigned to receive either IV lidocaine or a saline placebo (with the nerve b…

This study looked at whether a continuous nerve block (a small tube that delivers numbing medicine for days) can improve pain control and reduce opioid use after knee replacement surgery. Sixty adults having same-day knee replacement were enrolled. The goal was to see if this app…

This completed trial tested a new device called the NEUROCUPLE™ patch, which uses nanotechnology to reduce pain after knee replacement surgery. 156 adults were randomly assigned to receive either the active patch or a placebo patch for 30 days. The goal was to see if the patch co…

This study looked at whether using a forced-air warming blanket during knee replacement surgery helps prevent hypothermia (low body temperature) and related problems like shivering. Researchers compared 240 patients who either got the warming blanket or standard care. The goal wa…

This study tested whether a simulation-based education session before knee replacement surgery could lower patients' fear of the operation and fear of moving afterward. 48 adults scheduled for knee replacement were randomly assigned to either the simulation training or standard v…

This study tested whether Benson's relaxation exercise, a simple technique involving deep breathing and focusing on a meaningful word, could reduce anxiety and fear of movement (kinesiophobia) in 64 people who had total knee replacement. Participants practiced the exercise, and r…

This study tested whether dronabinol, a drug similar to cannabis, can help reduce the need for opioid painkillers after total knee replacement. 114 adults scheduled for knee surgery were randomly given either dronabinol or a placebo before and after their operation. Researchers m…

This study tested whether a specific leg exercise (quadriceps sets) helps people recover better after total knee replacement. Thirty-six patients who had surgery one month to one year earlier did either the quad exercise or standard physical therapy twice a week for four weeks. R…

This study tested a WeChat mini-program that provides personalized rehab plans, progress tracking, and emotional support for people recovering from hip or knee replacement surgery. 140 adults aged 18-80 used the app alongside standard care, or standard care alone. The goal was to…

This study looked at whether telehealth follow-up (phone or video calls) after total knee replacement helps patients regain function, take care of themselves, and do daily activities better than standard discharge instructions. About 60 adults who had knee replacement surgery wer…

This study tested three simple distraction methods—virtual reality headset, a squishy squeeze toy, and poetry reading—to see if they could help control pain after total knee replacement surgery. 140 adults were split into four groups, with three trying one of the distractions and…

This study tested whether using 10 mL or 20 mL of numbing medicine around the knee after replacement surgery could reduce the need for strong painkillers. 120 adults having knee replacement took part. The goal was to see if the smaller dose works just as well, with less medicatio…

This pilot study tested whether radiofrequency ablation (RFA) of the genicular nerves can reduce chronic knee pain in people who had a total knee replacement at least a year ago. Five participants with moderate to severe pain received the procedure. The goal was to see if RFA pro…

This study tested two types of nerve blocks to control pain after total knee replacement. 62 patients received either a new para-sartorial block or a standard femoral-sciatic block. The goal was to see which provides better pain relief with less muscle weakness. Results will help…

This study tested Emotional Freedom Technique (EFT), a therapy that combines talking with tapping on acupuncture points, to see if it helps with pain and anxiety after total knee replacement. 80 patients were enrolled, and their pain and anxiety levels were measured on the first …

This study tested whether the drug duloxetine, typically used for depression, can help reduce pain and the need for opioids after knee replacement surgery. Researchers enrolled 241 adults undergoing knee replacement and gave them either duloxetine or a placebo. The goal was to se…

This study looks at how three types of Journey II knee replacements (BCS, CR, and XR) move inside the body during activities like bending. Researchers will use video and sound recordings to measure joint motion in people who had knee replacement surgery at least six months ago. T…

This study looked at how spinal and general anesthesia change the heart's electrical activity in people having knee replacement surgery. Researchers measured heart signals before and after surgery in 140 adults. The goal was to see if one type of anesthesia affects the heart diff…

This study followed 294 knee replacement patients to see how often they experienced sudden, severe pain after their nerve block wore off. Researchers tracked pain levels, sleep quality, and patient satisfaction. The goal was to better understand this 'rebound pain' and improve pa…

This study looked at whether placing a drain after knee replacement surgery affects how much hemoglobin drops and whether patients need a blood transfusion. 102 patients were randomly assigned to get a drain or not. The goal is to see if drains help or hurt in terms of blood loss…

This study looked at whether heart rate variability (HRV) can predict rebound pain after total knee replacement. Rebound pain is a sudden, intense pain that can occur when nerve blocks wear off. Researchers measured HRV before and after surgery in 110 patients and tracked their p…

This study looked at 207 people who had knee replacement surgery to see if removing the surgical drain before or after the first physical therapy session makes a difference. The goal was to compare bleeding, complications, hospital stay, and pain. The results could help doctors d…

This study looked at 80 adults aged 45-85 having knee replacement under spinal anesthesia. Researchers checked their ECG before and after surgery to see if the anesthesia changed the heart's electrical axis. The goal was simply to observe and measure any changes, not to treat or …

This study looked back at 145 patients who had a knee replacement infection and underwent one of four surgical treatments. Researchers compared how often the infection came back or required another surgery. The goal is to help surgeons pick the best option for each patient.

This study looked at 118 people who had knee revision surgery using Medacta's 3D metal cones to support the bone. Researchers measured pain, function, and how often patients 'forgot' about their new knee. The goal was to see if the cones help the knee work better and last longer.…

This study looked at 33 patients who had total knee replacement surgery to see if their recovery scores at 6 hours were similar to those at 24 hours. The goal was to understand if patients could be safely discharged earlier. Researchers used a standard scoring system to measure r…