TOTAL KNEE ARTHROPLASTY
Clinical trials for TOTAL KNEE ARTHROPLASTY explained in plain language.
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Knee surgery blood mystery: does a drain help or hurt?
Disease control CompletedThis study looked at whether using a surgical drain during knee replacement surgery affects how much blood patients lose. Researchers compared 102 patients who got a drain to those who did not, measuring their blood levels after surgery. The goal was to see if using a drain chang…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Shifa International Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Study reviews High-Tech knee revisions for failed replacements
Disease control CompletedThis study looked back at the results for 118 patients who had a complex second knee replacement surgery. The surgery used a special implant system with metal cones to reinforce bone that was damaged or weak from a previous failed knee replacement. Researchers collected patient s…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Medacta International SA • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Tapping away knee surgery pain? study tests emotional technique
Symptom relief CompletedThis study tested whether the Emotional Freedom Technique (EFT), a mind-body practice involving tapping on acupressure points, could help reduce pain and anxiety after total knee replacement surgery. Researchers worked with 80 patients, teaching the technique to one group and com…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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New nerve block technique tested for knee surgery pain relief
Symptom relief CompletedThis study compared two different nerve block techniques for managing pain after knee replacement surgery. Researchers tested whether a newer method called PASC block works as well as a standard combination of nerve blocks. They measured how much pain medication patients needed i…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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New hope for knee replacement pain? tiny study tests Nerve-Zapping procedure
Symptom relief CompletedThis small pilot study tested whether a procedure called genicular nerve radiofrequency ablation (RFA) could reduce chronic pain in people who still had knee pain more than a year after a total knee replacement. The procedure uses heat to temporarily disable specific nerves aroun…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: University of Utah • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Simple exercise could ease pain for new knee patients
Symptom relief CompletedThis study tested whether a specific thigh-strengthening exercise helps people recover after total knee replacement surgery. It involved 36 patients who had their surgery within the past year. Researchers measured if the exercise reduced pain and improved knee strength, movement,…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Does drain timing speed up knee surgery recovery?
Symptom relief CompletedThis study looked at whether the timing of removing a surgical drain affects early recovery after knee replacement surgery. Researchers observed 207 patients with knee osteoarthritis who had a drain placed during surgery. They compared outcomes for patients who had the drain remo…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Knee surgery pain relief: does more numbing medicine mean less opioids?
Symptom relief CompletedThis study tested whether using 20 mL of numbing medicine instead of 10 mL in a specific leg nerve block would reduce patients' need for opioid painkillers after total knee replacement surgery. 120 patients having knee replacement surgery were randomly assigned to receive one of …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Regionshospitalet Silkeborg • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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New patch could slash opioid use after knee surgery
Symptom relief CompletedThis study tested a special patch called NEUROCUPLE™ designed to help manage pain after knee replacement surgery. Researchers wanted to see if wearing the patch for 30 days could reduce patients' pain and their need for strong opioid painkillers. They compared the active patch ag…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: nCap Medical • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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New study tests simpler pain relief for knee replacements
Symptom relief CompletedThis study compared two methods for managing pain after knee replacement surgery. Researchers tested whether an intravenous lidocaine drip works as well as a targeted nerve block for reducing pain and opioid use after surgery. The trial involved 120 patients who were randomly ass…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Phone calls for better knees: telehealth tested for recovery after surgery
Symptom relief CompletedThis study tested whether 14 days of phone-based nursing support helps people recover better after knee replacement surgery. Researchers compared patients who received telehealth education and counseling to those who got standard discharge instructions only. They measured improve…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Sakarya Applied Sciences University • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Virtual reality and poetry tested as Drug-Free pain relief after knee surgery
Symptom relief CompletedThis study tested whether simple distraction methods could help adults manage pain after knee replacement surgery. Researchers compared using a virtual reality headset, squeezing a squishy toy, or reading poetry to standard care alone. The main goal was to see if these activities…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Izmir Tinaztepe University • Aim: Symptom relief
Last updated Mar 19, 2026 14:55 UTC
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New hope for less painful knee replacements?
Symptom relief CompletedThis study tested if the medication duloxetine could help reduce pain and the need for opioid painkillers after total knee replacement surgery. It involved 241 adults having knee replacement for arthritis, including some with a condition that makes them extra sensitive to pain. P…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC
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Study looks back to find best fix for infected artificial knees
Knowledge-focused CompletedThis study looked back at the medical records of 145 patients who had surgery for an infected knee replacement. Researchers compared four different surgical approaches to see which one resulted in the fewest repeat infections and fewest additional surgeries. The goal is to help d…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Doctors track Heart's electrical signals during knee surgery
Knowledge-focused CompletedThis study observed 80 patients undergoing knee replacement surgery to see if spinal anesthesia changes the heart's electrical pattern. Researchers compared heart tracings taken before and after surgery to understand how this common anesthesia affects the heart. The study didn't …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Sevim Şenol Karataş • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Heartbeat holds clue to agony after knee surgery
Knowledge-focused CompletedThis study looked at whether a person's heart rate patterns before and after knee replacement surgery could predict who might experience a sudden, severe pain flare-up after their initial pain block wears off. Researchers monitored 110 patients undergoing planned knee replacement…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Konya City Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Researchers test when knee surgery patients are ready to go home
Knowledge-focused CompletedThis study aimed to understand when patients are ready to leave the hospital after knee replacement surgery. Researchers compared a standard recovery scoring system at 6 hours and 24 hours after the procedure. The goal was to gather information that could help improve discharge t…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Thammasat University Hospital • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC