Shake it off: vibration therapy may boost bone health after knee surgery

NCT ID NCT06988033

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether whole-body vibration therapy, alone or combined with exercise, can improve bone health and physical function in women with low bone density who have had a total knee replacement. Forty-eight women will be randomly assigned to vibration only, vibration plus exercise, or standard rehab. Researchers will measure bone turnover markers, mobility, strength, and pain over 12 weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Whole-body vibration therapy
What this could lead to
If it works, this could point toward a simple, drug-free way to help women regain strength and protect bone after knee replacement.
What could go wrong
This is a small, early-stage trial with only 48 participants. The vibration protocols are experimental, and results may not apply to all patients. There is also a risk that adding vibration does not improve outcomes over standard rehab.

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sultan 2. Abdulhamid Han Training and Research Hospital

    Istanbul, Uskudar, 34668, Turkey (Türkiye)

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