TOTAL KNEE ARTHROPLASTY
Clinical trials for TOTAL KNEE ARTHROPLASTY explained in plain language.
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Knee implants tracked for 10 years after surgery
Disease control OngoingThis study follows 118 people who already received a LEGION knee implant during total knee replacement surgery. Researchers will check how well the implants hold up over 10 years by measuring implant survival and patient quality of life using questionnaires. The goal is to confir…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Knee implant study tracks 10-Year performance
Disease control OngoingThis study looks at how well a specific knee replacement implant works over 10 years. Researchers are checking the safety and performance of the Legion knee implant in 126 people who already received it. The goal is to see how long the implant lasts and if it helps patients with …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Knee replacement pain study: which injection works best?
Symptom relief ENROLLING_BY_INVITATIONThis study compares two methods of giving the pain medicine EXPAREL during knee replacement surgery. About 40 adults will receive the medicine either as a targeted block or as local infiltration. Participants will report their pain levels and any extra pain medicines they need. T…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New pain pumps aim to ease recovery after knee replacement
Symptom relief ENROLLING_BY_INVITATIONThis study compares two types of pain-relief pumps placed inside the knee joint after total knee replacement. 65 adults having outpatient knee surgery will be randomly assigned to receive either standard pain management or one of two pump brands. The goal is to see which approach…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Pre-Surgery workout may ease knee replacement recovery
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a guided exercise program done at home before knee replacement surgery can help people recover better. 84 adults scheduled for knee replacement will be asked to do simple exercises daily from the day they are admitted until surgery. Researchers will measu…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Anna Sun • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Smart glasses may speed up pain relief for knee surgery patients
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether doctors using smart glasses can perform a saphenous nerve block (a pain-relieving injection) faster and more accurately for knee replacement patients. About 100 adults having knee surgery will be enrolled. The goal is to see if the glasses reduce procedur…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: MetroHealth Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Smart knee implant tracks your steps to speed recovery
Knowledge-focused OngoingThis study follows 200 people who received a smart knee implant (Persona IQ) that tracks movement after total knee replacement. The goal is to see if data from the implant and a phone app can help doctors understand recovery and spot problems early. Participants use a smartphone …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Knee replacement showdown canceled before it started
Knowledge-focused TerminatedThis study aimed to compare knee movement in people who had one of two different total knee replacements. Researchers planned to measure how the knee bends and shifts during activities like stepping up and deep knee bends. The study was withdrawn before any participants were enro…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Knee surgery showdown: does the cutting tool overheat your bone?
Knowledge-focused OngoingThis study looks at how hot bone gets during total knee replacement surgery when using a burr (robotic) versus a saw (conventional). Twenty patients will have their bone temperature measured with an infrared thermometer during the procedure. The goal is simply to compare the heat…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: East Suffolk and North Essex NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Knee replacement study pulled before it even started
Knowledge-focused TerminatedThis study was designed to compare how well patients recover after total knee replacement using either the Newton Knee protocol (with computer navigation) or traditional manual instruments. Researchers planned to measure satisfaction, pain, function, hospital stay length, and use…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Newton-Wellesley Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Knee replacement patients: do your pain catheters stay put?
Knowledge-focused OngoingThis study watches 100 knee replacement patients to see if a thin tube that delivers pain medicine near the thigh stays in the right place the day after surgery. Doctors will use ultrasound to check the tube's position and look for reasons it might move or stop working. The goal …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:29 UTC