TOTAL KNEE ARTHROPLASTY
Clinical trials for TOTAL KNEE ARTHROPLASTY explained in plain language.
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Pill power: could extra days of a common drug speed up knee surgery recovery?
Symptom relief Not yet recruitingThis study is testing whether taking oral tranexamic acid (TXA) pills for 3 or 7 days after a total knee replacement helps patients recover better. Researchers want to see if this extended use improves pain, knee movement, and overall function in the weeks and months after surger…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New study aims to find best pain block for knee surgery recovery
Symptom relief Not yet recruitingThis study aims to find which combination of nerve-blocking injections provides better pain relief and helps patients move easier after total knee replacement surgery. Researchers will compare two different injection techniques in 50 patients. The goal is to reduce pain, lower op…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Konya Beyhekim Training and Research Hospital • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Brain and body workout tested for better knee recovery
Symptom relief Not yet recruitingThis study aims to see if adding mental tasks to standard physical exercises helps people recover better after knee replacement surgery. It will compare two groups of 40 adults aged 50-65: one doing regular exercises and another doing exercises that also challenge their thinking.…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Can special sounds ease surgery pain?
Symptom relief Not yet recruitingThis study is testing whether listening to binaural beats (special audio tones) or music of your choice can help reduce pain and anxiety right after knee or hip replacement surgery. Researchers will compare these audio methods in 50 adults recovering from surgery. They will measu…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: University of Miami • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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New nerve block technique aims to ease pain after knee surgery
Symptom relief Not yet recruitingThis study aims to find the best way to manage pain after knee replacement surgery. Researchers will compare two different pain control techniques in 80 patients undergoing the procedure. One method involves injections around the surgical site, while the other uses targeted nerve…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Mar 24, 2026 12:03 UTC
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VR headsets could be the new painkiller for knee surgery recovery
Symptom relief Not yet recruitingThis study is testing if watching a relaxing nature video through a virtual reality headset can help people feel less pain and anxiety during their physical therapy after a knee replacement. Researchers will compare 102 patients who use VR during their therapy to those who receiv…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: Celal Bayar University • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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One shot before surgery could cut painkiller use for weeks
Symptom relief Not yet recruitingThis study is testing whether a single dose of methadone given right before knee replacement surgery can improve pain control and reduce the need for other pain medications in the weeks after the operation. Researchers will compare pain levels, opioid use, side effects, and recov…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE4 • Sponsor: AdventHealth • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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New nursing approach aims to ease stress for knee replacement patients and families
Symptom relief Not yet recruitingThis study is testing a special nursing program designed to help people cope better with the stress of recovering from total knee replacement surgery. The program focuses on helping patients understand their stress, use family and social support, and build mental strength. Resear…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Symptom relief
Last updated Mar 17, 2026 13:09 UTC
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Knee surgery recovery: does how you get your steroid pill matter?
Symptom relief Not yet recruitingThis study aims to see if the way a common steroid (dexamethasone) is given—by mouth or through an IV—affects pain and recovery right after knee replacement surgery. It will observe 99 patients who are already scheduled for surgery, following their normal doctor's plan without ch…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Sponsor: Haseki Training and Research Hospital • Aim: Symptom relief
Last updated Mar 12, 2026 13:51 UTC
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New nerve block could ease pain after knee surgery
Symptom relief Not yet recruitingThis study aims to see if a new combination of four nerve blocks provides better pain relief after knee replacement surgery compared to the current standard method. Researchers will enroll 100 adults with knee arthritis who are scheduled for knee replacement. They will measure re…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Mar 02, 2026 15:28 UTC
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Doctors test blue dye to find best washout for infected knee replacements
Knowledge-focused Not yet recruitingThis small pilot study aims to find out how much sterile fluid is needed to visibly clean out contamination during surgery for an infected knee replacement. Researchers will use a safe blue dye during surgery to simulate germs and measure how much washing it takes for the dye to …
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: PHASE1 • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Surgeons test 3D-Printed device to Fine-Tune knee replacements
Knowledge-focused Not yet recruitingThis study is testing a new 3D-printed tool that helps surgeons measure how balanced a new knee joint is during replacement surgery. It will be used on 50 patients getting their first knee replacement. The goal is to see if this tool is useful for gathering information, but it wo…
Matched conditions: TOTAL KNEE ARTHROPLASTY
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC