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Knee surgery pain relief: could a simple nerve block cut opioid use?

NCT ID NCT07589127

Not yet recruiting Symptom relief Sponsor: Helse Møre og Romsdal HF Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether a genicular nerve block given before knee replacement surgery can reduce pain and the need for opioids. About 70 adults with knee osteoarthritis will receive either the nerve block or a placebo injection. Researchers will track pain levels, opioid use, and recovery for three months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ropivacaine (local anesthetic)
What this could lead to
If it works, this could offer a simple way to reduce pain and opioid use after knee replacement surgery.
What could go wrong
This is a small, early-stage trial with only 70 participants, so results may not apply to everyone. The nerve block may not provide significant benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GENICULAR NERVE BLOCK OSTEOARTHRITIS (OA) OF THE KNEE TOTAL KNEE ARTHROPLASTY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nordmøre and Romsdal Hospital (SNR)

    Hjelset, Møre og Romsdal, 6412, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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