Heartbeat clues may forecast sudden Post-Surgery pain
NCT ID NCT06977191
First seen Jan 23, 2026 · Last updated Jun 20, 2026 · Updated 26 times
Summary
This study looked at whether heart rate variability (HRV) can predict rebound pain after total knee replacement. Rebound pain is a sudden, intense pain that can occur when nerve blocks wear off. Researchers measured HRV before and after surgery in 110 patients and tracked their pain levels. The goal is to see if HRV can help doctors personalize pain management after knee surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Konya City Hospital
Konya, 42090, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors identify patients at risk for rebound pain after knee replacement and tailor pain treatments to each person.
What could go wrong
This is a small, completed observational study, not a treatment trial. The results may not apply to all patients or lead to a proven prediction tool.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.