Heartbeat clues may forecast sudden Post-Surgery pain

NCT ID NCT06977191

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether heart rate variability (HRV) can predict rebound pain after total knee replacement. Rebound pain is a sudden, intense pain that can occur when nerve blocks wear off. Researchers measured HRV before and after surgery in 110 patients and tracked their pain levels. The goal is to see if HRV can help doctors personalize pain management after knee surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify patients at risk for rebound pain after knee replacement and tailor pain treatments to each person.
What could go wrong
This is a small, completed observational study, not a treatment trial. The results may not apply to all patients or lead to a proven prediction tool.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Konya City Hospital

    Konya, 42090, Turkey (Türkiye)

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