New procedure may ease knee pain after replacement surgery

NCT ID NCT05130216

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tested whether radiofrequency ablation (RFA) of the genicular nerves can reduce chronic knee pain in people who had a total knee replacement at least a year ago. Five participants with moderate to severe pain received the procedure. The goal was to see if RFA provides meaningful pain relief.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
radiofrequency ablation
What this could lead to
If it works, this could offer a non-surgical option for people with lingering knee pain after joint replacement.
What could go wrong
This was a very small pilot study with only 5 people, so results may not apply to everyone. The procedure also carries risks like infection or nerve damage.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Utah Orthopaedic Center

    Salt Lake City, Utah, 84108, United States

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