Can a Cannabis-Like drug cut opioid use after knee surgery?
NCT ID NCT04734080
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether dronabinol, a drug similar to cannabis, can help reduce the need for opioid painkillers after total knee replacement. 114 adults scheduled for knee surgery were randomly given either dronabinol or a placebo before and after their operation. Researchers measured opioid use, pain levels, and recovery time to see if dronabinol made a difference.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OPIOID USE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital for Special Surgery
New York, New York, 10021, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a 5-Pill opioid prescription match a 30-Pill one after hip surgery?
- Hidden risk: could opioid misuse be overlooked in cancer care?
- Can mindfulness curb opioid use after injury?
- Which nerve drug wins the battle against Post-Surgical knee pain?
- Can a single steroid dose transform knee replacement recovery?
- Can mindfulness after injury curb opioid dependence?