Knee replacement pain study: could a simple IV drug replace nerve blocks?

NCT ID NCT04828083

First seen Mar 25, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tested whether giving lidocaine through an IV works as well as a targeted nerve block for controlling pain after knee replacement surgery. 120 adults having a knee replacement took part. The goal was to see if the IV method could reduce the need for strong opioid painkillers while still providing good pain relief and recovery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ARTHROPLASTY, REPLACEMENT, KNEE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

Conditions

Explore the condition pages connected to this study.