PROSTATE ADENOCARCINOMA

This study tested if a shorter, more intense radiation schedule (5 weeks) works as well as the standard longer schedule (7 weeks) for men who had surgery for prostate cancer. The main goal was to see if the shorter treatment caused fewer bowel and urinary side effects while still…

This study tested whether giving prostate cancer survivors more frequent and detailed care plans would improve their follow-up health checks. The goal was to help men who had radiation and hormone therapy get better coordinated care between their cancer doctors and primary care p…

This study tested a shorter, more intense form of radiation therapy for men whose prostate cancer had a high risk of returning after surgery. The goal was to see if this faster treatment schedule worked as well as standard, longer radiation at keeping the cancer from coming back,…

This study tested a combination of two drugs, talazoparib and temozolomide, for men with advanced prostate cancer that had spread and stopped responding to standard hormone therapies. The first part of the study aimed to find the safest dose, and the second part tested how well t…

This study tested a new type of internal radiation treatment for prostate cancer. Doctors placed tiny radioactive seeds directly into the tumor before a patient's scheduled surgery. The main goal was to see if this procedure was safe and practical to perform.

This small pilot study tested a new, targeted laser treatment for men with low-to-intermediate risk prostate cancer. Using real-time MRI guidance, doctors aimed to precisely heat and destroy only the cancerous tumor area, sparing the rest of the prostate. The main goals were to s…

This study tested a two-drug combination for men with advanced prostate cancer that had stopped responding to standard hormone-blocking treatments. Researchers gave patients high doses of testosterone along with a drug called olaparib, which blocks cancer cells from repairing dam…

This study tested whether the drug niraparib could help control advanced prostate cancer in men with specific genetic defects. The trial included 11 men whose cancer had stopped responding to standard hormone treatments but had responded to platinum chemotherapy. Researchers want…

This first-in-human study tested the safety of a new dye called Illuminare-1, which is designed to glow and highlight nerve structures during prostate cancer surgery. The goal is to help surgeons see and avoid damaging important nerves, which can lead to side effects like inconti…

This study tested a new type of medical scan to better find prostate cancer that has returned after initial surgery or radiation. About 235 men whose blood tests showed their cancer might be back received an injection of a special tracer and then had a PET/CT scan. The goal was t…

This small pilot study tested whether a structured diet and exercise program could help men with prostate cancer avoid harmful side effects from their main treatments. The treatments (radiation and hormone therapy) can cause weight gain, muscle loss, and insulin resistance. Resea…