PROSTATE ADENOCARCINOMA

This study tested a new type of radiation therapy for prostate cancer. Doctors placed tiny radioactive seeds directly into the tumor to see if it was safe and possible to do before surgery. Only one person took part, and the main goals were to check if the seeds could be placed c…

This study tested a combination of two drugs, talazoparib and temozolomide, in 16 men with advanced prostate cancer that had spread and stopped responding to hormone therapy. The goal was to find the safest dose and see if the drugs could shrink tumors. The treatment is not a cur…

This study tested a shorter course of radiation (hypofractionation) in 52 men with prostate cancer who had high-risk features after their prostate was removed. The goal was to see if giving higher doses over fewer sessions could better control the cancer and reduce side effects. …

This study tested a drug called niraparib in 11 men with advanced prostate cancer that was no longer responding to hormone therapy. All participants had previously received platinum chemotherapy and had specific DNA repair defects. The goal was to see if niraparib could slow canc…

This study looked at whether adding a drug called niraparib to the usual treatment (radiation plus hormone therapy) can help prevent high-risk prostate cancer from growing or coming back. Niraparib works by blocking a repair process that cancer cells rely on, causing them to die.…

This study tested whether a shorter, more intense radiation schedule (hypofractionated) works as well as the standard longer schedule after prostate cancer surgery. About 296 men who had their prostate removed took part. The goal was to see if the shorter treatment could control …

This small pilot study tested a new way to treat low-risk prostate cancer using MRI-guided laser ablation. Seven men with early-stage prostate cancer received the treatment to see if it was safe and could successfully destroy tumors. The goal was to control the disease with fewer…

This study tested a new combination treatment for men with a type of advanced prostate cancer that no longer responds to standard hormone therapy. The treatment uses testosterone (given as shots) along with a drug called olaparib, which blocks cancer cells from repairing damage. …

This study tested a new type of PET/CT scan using a radioactive tracer called copper Cu 64 PSMA I&T to find prostate cancer that has come back after initial treatment. The study involved 235 men with rising PSA levels after surgery or radiation. The goal was to see how accurately…

This study tested a new dye called Illuminare-1 that makes nerves glow during prostate cancer surgery. The goal was to find a safe dose that helps surgeons avoid damaging nerves, which can cause side effects like incontinence or erectile dysfunction. The trial involved 41 men hav…

This early-stage study tested a precise, high-dose radiation technique called SBRT in 42 adults with breast, lung, or prostate cancer that had spread to several places in the body. The main goal was to find the safest dose and check for side effects. Researchers hope this approac…

This study tested whether a diet and physical activity program could help prevent or reduce metabolic side effects (like weight gain, insulin resistance, and unhealthy cholesterol levels) caused by hormone therapy in men with prostate cancer. Twenty men undergoing radiation plus …

This study looked at whether giving prostate cancer survivors more detailed survivorship care plans helps them get better follow-up care for heart health. The study involved 550 men who had radiation and hormone therapy, which can raise the risk of diabetes and heart problems. Re…