New combo therapy shows promise for tough prostate cancers

NCT ID NCT03910660

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new drug (BXCL701) combined with an immunotherapy (pembrolizumab) in 98 men with advanced prostate cancer that no longer responds to hormone therapy. The goal was to see if the combination could shrink tumors or slow the disease. This is a disease control approach, not a cure, as ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma neuroendocrine neoplasm prostate adenocarcinoma prostate cancer prostate small cell carcinoma small cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BioXcel Clinical Research Site

    Denver, Colorado, 80211, United States

  • BioXcel Clinical Research Site

    Detroit, Michigan, 48201, United States

  • BioXcel Clinical Research Site

    Glasgow, England, G12 0YN, United Kingdom

  • BioXcel Clinical Research Site

    London, Great Britain, W1T 7HA, United Kingdom

  • BioXcel Clinical Research Site

    Sutton, Surrey, SM2 5NG, United Kingdom

  • Center for Advanced Medicine / R.J. Zuckerberg Cancer Center (Northwell Health Cancer Institute)

    Lake Success, New York, 11042, United States

  • Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • University of California San Francisco (UCSF)

    San Francisco, California, 94158, United States

  • Weill Cornell Medicine New York

    New York, New York, 10021, United States

  • White Plains Hospital Center for Cancer Care

    White Plains, New York, 10601, United States

  • Yale University

    New Haven, Connecticut, 06510, United States