Glow-in-the-Dark dye could help surgeons spot hidden prostate cancer

NCT ID NCT05946603

Completed Diagnosis Sponsor: Intuitive Surgical Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a fluorescent dye called IS-002 that makes prostate cancer cells glow under special lights during robotic surgery. Fifty-nine men with prostate cancer received the dye before surgery, and surgeons used a special camera to see the glowing areas. The goal was to see if this helps remove all cancer and reduce leftover cancer cells at the surgical edges.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: IS-002 (a fluorescent dye)
What this could lead to: If successful, this could help surgeons remove prostate cancer more completely during robotic surgery, potentially lowering the chance of leftover cancer cells.
What could go wrong: This is a small, early feasibility study (59 people) and the dye may not reliably highlight all cancer tissue. It is not a treatment itself, only a visual aid.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Johns Hopkins

Baltimore, Maryland, 21287, United States
MSKCC

New York, New York, 10065, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
UCSF

San Francisco, California, 94158, United States

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