Could a tiny dose of this pill help men with prostate cancer avoid the knife?
NCT ID NCT04530552
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 25 times
Summary
This study tests whether a very low dose of the drug apalutamide, taken for 3-4 weeks before prostate removal surgery, can lower PSA levels in men with early-stage prostate cancer. The goal is to see if such a low dose is effective enough to potentially allow men to delay or avoid surgery or radiation in the future. The trial involves 34 men whose cancer is still confined to the prostate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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George Washington University Medical Center
Washington D.C., District of Columbia, 20037, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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NCI - Center for Cancer Research
Bethesda, Maryland, 20892, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of Arizona Cancer Center - Prevention Research Clinic
Tucson, Arizona, 85719, United States
Conditions
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