New combo attack on returning prostate cancer shows promise
NCT ID NCT03796767
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This phase 2 trial is testing whether surgery and radiation can help men whose prostate cancer has come back and spread to a few spots in the body. About 20 participants will receive either surgery to remove the spread tumors or targeted radiation, or both. The main goal is to see if this approach can lower PSA levels by at least half six months after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- surgery (metastasectomy) and radiation therapy (hypofractionated radiation, IMRT, stereotactic body radiation therapy)
- What this could lead to
- If successful, this could offer a way to control recurrent prostate cancer that has spread to a few spots, potentially delaying disease progression.
- What could go wrong
- This is a small early-phase trial with only 20 participants, so results may not apply to everyone. The treatment involves surgery and radiation, which carry risks like infection, pain, or damage to nearby tissues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can surgery boost control of spread prostate cancer?
- Can a better scan sharpen radiation for prostate cancer?
- Hormone therapy showdown: can an oral pill beat the shot for prostate cancer patients?
- Can tracking tumor movement during radiation make treatment more precise?
- Can a single small incision preserve sexual function after prostate cancer surgery?
- Can a shorter course of radiation tame prostate cancer with fewer side effects?