New drug shows promise for Hard-to-Treat prostate cancer

NCT ID NCT04288687

First seen Mar 12, 2026 · Last updated May 12, 2026 · Updated 6 times

Summary

This study tested a drug called niraparib in 11 men with advanced prostate cancer that was no longer responding to hormone therapy. All participants had previously received platinum chemotherapy and had specific DNA repair defects. The goal was to see if niraparib could slow cancer growth and lower PSA levels. Results suggest it may help control the disease, but more research is needed.

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Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.