Promising drug shows hope for Hard-to-Treat prostate cancer

NCT ID NCT04288687

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a drug called niraparib in 11 men with advanced prostate cancer that was no longer responding to hormone therapy but had recently been treated with platinum chemotherapy. The goal was to see if niraparib could keep the cancer from growing for at least 6 months. The approach targets cancers with specific DNA repair defects, aiming to control the disease rather than cure it.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States