PRESBYOPIA

This phase 3 study tested the long-term safety of LNZ101 eye drops, a combination of aceclidine and brimonidine, in 362 adults aged 45-75 with presbyopia (age-related blurry near vision). Participants used the drops regularly and were monitored for side effects. The study is comp…

This study looked at the long-term safety and performance of AcrySof PanOptix trifocal lenses in 211 people who had them implanted in both eyes 3 to 5 years earlier. Researchers checked vision and recorded any eye problems or device issues. The goal was to make sure these lenses …

This completed pilot study tested two different daily disposable multifocal contact lenses in 74 adults aged 40 to 70 with presbyopia. Participants wore each lens type for about a week, and researchers measured how well they could see at distance, intermediate, and near distances…

This study tested a newer trifocal lens implant (Clareon PanOptix Pro) against an older one (Clareon PanOptix) in 71 adults having cataract surgery in both eyes. Each person got one of each lens, so their eyes could be compared directly. The goal was to see if the newer lens prov…

This study checked the safety and effectiveness of the CorVision microlens, a tiny implant placed in the cornea to help with presbyopia (age-related difficulty seeing up close). About 95 people who had the implant in an earlier study came back for a single 4-year follow-up visit.…

This study tested an eye drop called LNZ101 to help people with presbyopia (age-related trouble seeing up close) read without glasses. 469 adults aged 45-75 received the drops, and researchers measured how many gained clear near vision without losing distance vision on the first …

This study compared two types of soft multifocal contact lenses (Proclear 1 Day and Clariti 1 Day) to see which one people liked better. 67 adults who already wore contact lenses and needed reading glasses tried both lenses and rated their overall satisfaction. The goal was to he…

This Phase 2 trial tested three different eye drop formulas—BRIMOCHOL, BRIMOCHOL F, and carbachol alone—to see if they could improve near vision in people with presbyopia (age-related difficulty seeing up close). The study enrolled 18 adults who received a single drop in each eye…

This study tested whether a special eye drop (esculin and digitalis glycosides) can improve near vision in people with presbyopia, the age-related difficulty focusing on close objects. 62 adults aged 40-55 took part. The goal was to see if the drops help the eye's focusing muscle…

This study tested a special lens implant (EVO+ Visian ICL) to improve near vision in 41 adults with presbyopia, an age-related condition that makes it hard to see up close. The lens is placed behind the iris and in front of the eye's natural lens. Six months after surgery, most e…

This completed Phase 3 trial tested whether phentolamine eye drops (Nyxol) can improve near vision in people with presbyopia, the age-related loss of ability to focus on close objects. 569 adults aged 45 to 64 used the drops or a placebo once daily for 8 days. The main goal was t…

This Phase 3 trial tested Nyxol eye drops, alone or with low-dose pilocarpine, in 333 adults aged 40–64 with presbyopia (age-related difficulty seeing up close). The goal was to improve near vision without losing distance vision. Participants received drops and were measured afte…

This study tested a special type of artificial lens (TECNIS Eyhance IOL) in 62 adults aged 45-75 who had cataract surgery. The goal was to see how well the lens helps people see clearly at different distances, from close up to far away. Researchers measured vision at nine distanc…

This study looked at 40 people over 45 who had cataract surgery with a special lens that helps with both near and far vision. Half of them had the surgery with digital assistance, and half without. The goal was to see if the digital help led to better vision or more satisfaction …

This Phase 3 trial tested LNZ101 eye drops in 229 people aged 45-75 with presbyopia, a condition that makes it hard to see up close. The drops combine aceclidine and brimonidine to temporarily improve near vision. The main goal was to see if participants could read three lines be…

This study tested whether a daily berry extract supplement (from aronia, honeyberry, and bilberry) could improve vision in 27 adults aged 50+ with presbyopia (age-related blurry near vision). Participants took the supplement or a placebo for 6 weeks each, with a 5-week break in b…

This study tested a low-energy femtosecond laser (the Perfector device) to treat presbyopia in 19 people who already had monofocal lens implants from cataract surgery. The goal was to improve near and intermediate vision without harming distance vision. Participants were measured…

This study looked at two different artificial lenses used during cataract surgery to see which one gives better vision at near, middle, and far distances. 80 adults with cataracts received one of the two lenses. The goal was to find out if one lens helps people see better without…

This study tested new multifocal contact lenses designed for people with both presbyopia (age-related blurry near vision) and astigmatism (blurry vision due to an irregularly shaped cornea). 95 habitual contact lens wearers wore the lenses for 30 days, and researchers measured ho…

This study tested a special lens implant (EVO+ Visian ICL) in 47 adults to correct or reduce nearsightedness, farsightedness, astigmatism, and age-related reading problems (presbyopia). The lens was placed inside the eye to improve vision at all distances without removing the nat…

This study tested two different trifocal lens implants used during cataract surgery to see which one gives better vision. 87 people who needed cataract surgery in both eyes received one type of lens in each eye. The main goal was to measure how clearly they could see letters on a…

This study tested a new daily disposable contact lens designed for people with astigmatism (blurry vision from an irregularly shaped cornea) and presbyopia (age-related difficulty seeing up close). 176 adults aged 40-70 wore the lens for one week. Researchers measured how well th…

This study tested two different multifocal contact lenses in 106 people with presbyopia, an age-related condition that makes it hard to see up close. Participants wore each lens for a week to see how well they could see at different distances. The goal was to compare the performa…

This study tested whether a combination of two eye drops (Nyxol and pilocarpine) can help people with presbyopia—age-related difficulty seeing up close—read better without glasses. About 150 adults aged 40 to 64 took part. The main goal was to see how many people could read 15 or…

This study tested whether using a red-light device twice a day for a month can reduce visual fatigue in people aged 40 and older with presbyopia (age-related difficulty seeing up close). Sixty-six participants either used the real device or a sham device. Researchers measured cha…

This early-phase study tested whether a new eye drop called NV701 works better than the existing drop Vuity for shrinking pupil size in people with presbyopia (age-related blurry near vision). Fifty-five adults aged 40-55 received one dose of each drop in different eyes. Research…

This study checked if a smartphone app called VisionApp can accurately measure vision problems like nearsightedness and presbyopia (age-related reading difficulty). Sixteen adults aged 40 and older used the app at home, and their results were compared to standard eye exams. The g…

This study compared two different optical devices that measure the eye before cataract or presbyopia surgery. 133 patients had their eyes measured with both devices to see if the measurements matched. The goal was to help doctors choose the best tool for planning lens implants.