NEUROBLASTOMA
Clinical trials for NEUROBLASTOMA explained in plain language.
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First pediatric trial tests promising cancer pill for kids Who've run out of options
Disease control CompletedThis early-stage study tested a new oral medication called CUDC-907 in children and young adults whose cancers had returned or stopped responding to standard treatments. The main goals were to check for side effects and find the safest dose for children, since this drug had only …
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New immunotherapy combo aims to keep deadly childhood cancer from returning
Disease control CompletedThis study tested whether a combination of immunotherapy drugs (Hu3F8 and GM-CSF) plus a vitamin A-like drug (isotretinoin) could help prevent cancer from coming back in children with high-risk neuroblastoma who had achieved their first remission. The trial involved 59 patients w…
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for kids with Tough-to-Treat cancer
Disease control CompletedThis study tested a new oral drug called lorlatinib in children and adults with advanced neuroblastoma that had come back or stopped responding to other treatments. The main goals were to find a safe dose for children and to see how the body processes the drug. Researchers also l…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Scientists re-engineer immune cells to hunt childhood cancer
Disease control CompletedThis study tested a new treatment for children with high-risk neuroblastoma, a serious childhood cancer. Researchers modified patients' own immune cells to better recognize and attack cancer cells, hoping these 'supercharged' cells would last longer in the body than previous vers…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Can less radiation still fight childhood cancer?
Disease control CompletedThis study tested whether using a smaller dose of radiation could still effectively control high-risk neuroblastoma, a serious childhood cancer, while aiming to reduce long-term side effects. It involved 78 children and young adults who had already received chemotherapy and surge…
Matched conditions: NEUROBLASTOMA
Phase: EARLY_PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New hope for kids with tough cancers: Two-Step transplant trial
Disease control CompletedThis early-stage study tested a new two-step stem cell transplant method for children and young adults whose cancers had returned or didn't respond to standard treatments. The goal was to see if this approach, which uses specially processed cells from a partially matched family d…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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First test of 'Reinforced' immune cells for Kids' tough cancers
Disease control CompletedThis early-stage study tested a new immune therapy for children and young adults whose solid tumors did not respond to standard treatments. Doctors collected and grew a patient's own 'natural killer' (NK) immune cells, then gave them back to the patient to fight the cancer. The m…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Feb 17, 2026 14:35 UTC
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Scientists test DNA blueprint method to find better treatments for kids with tough cancers
Knowledge-focused CompletedThis study tested whether doctors could quickly analyze the genetic makeup of a child's tumor and use that information to choose a personalized treatment plan. It involved 186 children and young adults (up to age 21) whose cancers had returned or did not respond to standard treat…
Matched conditions: NEUROBLASTOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC