New hope for kids with tough neuroblastoma: blood vessel blocker shows promise

NCT ID NCT02308527

First seen May 12, 2026 · Last updated May 16, 2026 · Updated 1 time

Summary

This study tested whether adding bevacizumab (a drug that cuts off a tumor's blood supply) to standard chemotherapy helps children aged 1 to 21 with neuroblastoma that has come back or not responded to treatment. About 225 children took part. The goal was to see if the combination could shrink tumors or slow the disease. While not a cure, the approach aims to better control the cancer and improve outcomes.

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Contacts and locations

Locations

  • Hopital des Enfants

    Toulouse, 31059, France

  • Instituto de Investigacion Sanitaria

    Valencia, 46026, Spain

  • Natasha van Eijkelenburg

    Utrecht, Netherlands

  • Ospedale Pediatrico Bambino Gseu

    Rome, 00165, Italy

  • Our Ladys Children's Hospital Dublin

    Dublin, Dublin 12, Ireland

  • St Anna Children's Hospital and CCRI/Studies and Statistics

    Vienna, A-1090, Austria

  • Swiss Paediatric Oncology Group

    Bern, 3008, Switzerland

  • The Royal Marsden NHS Foundation Trust and Institute of Cancer Research

    Sutton, Surrey, SM2 5PT, United Kingdom

  • University Hospital

    Ghent, Belgium

  • University Hospital Rigshospitalet

    Copenhagen, DK-2100, Denmark

Conditions

Explore the condition pages connected to this study.