Radioactive cocktail shows promise against tough childhood cancer

NCT ID NCT00253435

First seen May 14, 2026 · Last updated May 16, 2026 · Updated 1 time

Summary

This study tested a treatment for children with high-risk neuroblastoma that had come back or not responded to standard therapy. It combined a radioactive drug (MIBG) with strong chemotherapy, followed by a stem cell transplant to restore blood cells. The goal was to see if this approach could shrink tumors and improve survival. Fifty children took part, and the main results were measured 60 days after the transplant.

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Contacts and locations

Locations

  • AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus

    Atlanta, Georgia, 30322, United States

  • C.S. Mott Children's Hospital at University of Michigan Medical Center

    Ann Arbor, Michigan, 48109-0286, United States

  • Children's Hospital and Regional Medical Center - Seattle

    Seattle, Washington, 98105, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104-4318, United States

  • Childrens Hospital Los Angeles

    Los Angeles, California, 90027-0700, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229-3039, United States

  • Cook Children's Medical Center - Fort Worth

    Fort Worth, Texas, 76104, United States

  • Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • Lucile Packard Children's Hospital at Stanford University Medical Center

    Palo Alto, California, 94304, United States

  • Morgan Stanley Children's Hospital of New York-Presbyterian

    New York, New York, 10032, United States

  • Texas Children's Cancer Center and Hematology Service at Texas Children's Hospital

    Houston, Texas, 77030-2399, United States

  • UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94143, United States

  • University of Chicago Comer Children's Hospital

    Chicago, Illinois, 60637, United States

  • University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

    Madison, Wisconsin, 53792-6164, United States

Conditions

Explore the condition pages connected to this study.